| Literature DB >> 8711208 |
Abstract
SRY is the gene that initiates the genetic cascade leading to testis development in mammals. Since its discovery in 1990 and the direct demonstration of its male-determining role in transgenic mice, attention has turned to understanding the biochemical mode of action of the SRY gene product, and to the identification of other genes in the sex-determining pathway. Recent progress in these efforts is summarized in this review.Entities:
Mesh:
Substances:
Year: 1995 PMID: 8711208 DOI: 10.1071/rd9950713
Source DB: PubMed Journal: Reprod Fertil Dev ISSN: 1031-3613 Impact factor: 2.311