Literature DB >> 870903

Effects of diazepam on behaviour suppressed by extinction in pigs.

R Dantzer.   

Abstract

Diazepam injected to pigs previously trained to perform an operant response for food according to a continuous reinforcement schedule significantly increased resistance to extinction compared to control pigs. In pigs submitted to a time-out procedure diazepam increased the number of nonreinforced responses at the beginning of the acquisition but was unable to disinhibit suppressed behaviour in the later stages of acquisition when the extinguished behaviour was well acquired. The results are discussed with respect to antiaversive or disinhibitory effects of benzodiazepines and an alternative interpretation, the strengthening of the prevailing behavioural tendency in the animal's repertoire at the time of test, is put forward.

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Year:  1977        PMID: 870903     DOI: 10.1016/0091-3057(77)90066-1

Source DB:  PubMed          Journal:  Pharmacol Biochem Behav        ISSN: 0091-3057            Impact factor:   3.533


  5 in total

1.  Behavioral analysis of diazepam-induced memory deficits: evidence for sedation-like effects.

Authors:  L E Kalynchuk; C H Beck
Journal:  Psychopharmacology (Berl)       Date:  1992       Impact factor: 4.530

2.  Reduced behavioral variability in extinction: effects of chronic treatment with the benzodiazepine, diazepam or with ethanol.

Authors:  C H Beck; E A Loh
Journal:  Psychopharmacology (Berl)       Date:  1990       Impact factor: 4.530

3.  [Effects of diazepam on exploratory behavior of pigs (author's transl)].

Authors:  R Dantzer
Journal:  Psychopharmacology (Berl)       Date:  1977-03-16       Impact factor: 4.530

4.  Increased resistance to satiation in diazepam-treated pigs.

Authors:  R Dantzer
Journal:  Experientia       Date:  1978-01-15

5.  Evaluating pharmacological models of high and low anxiety in sheep.

Authors:  Rebecca E Doyle; Caroline Lee; David M McGill; Michael Mendl
Journal:  PeerJ       Date:  2015-12-14       Impact factor: 2.984

  5 in total

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