Literature DB >> 870898

Current status of vitamin D metabolism.

A Fairney.   

Abstract

In summary one can record that the biochemist has discovered a beautiful metabolic pathway for vitamin D which is probably as yet incomplete. Subsequently the medicinal chemist has provided numerous synthetic analogues. However, delays in the diagnosis and treatment of vitamin D disorders, due to lack of specific assays and inadequate supplies of therapeutic metabolites, still unfortunately exist. It is hoped that these problems will be rectified as soon as more plentiful supplies of the appropriate metabolites are available.

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Year:  1977        PMID: 870898      PMCID: PMC1542933     

Source DB:  PubMed          Journal:  Proc R Soc Med        ISSN: 0035-9157


  10 in total

1.  Action of 1,25-dihydroxycholecalciferol, a potent, kidney-produced metabolite of vitamin D, in uremic man.

Authors:  A S Brickman; J W Coburn; A W Norman
Journal:  N Engl J Med       Date:  1972-11-02       Impact factor: 91.245

2.  Competitive protein-binding radioassay for 25-hydroxycholecalciferol.

Authors:  J G Haddad; K J Chyu
Journal:  J Clin Endocrinol Metab       Date:  1971-12       Impact factor: 5.958

3.  Filter assay for 1alpha, 25-dihydroxyvitamin D3. Utilization of the hormone's target tissue chromatin receptor.

Authors:  P F Brumbaugh; D H Haussler; K M Bursac; M R Haussler
Journal:  Biochemistry       Date:  1974-09-24       Impact factor: 3.162

4.  Unique biosynthesis by kidney of a biological active vitamin D metabolite.

Authors:  D R Fraser; E Kodicek
Journal:  Nature       Date:  1970-11-21       Impact factor: 49.962

5.  Seasonal variations in serum 25-hydroxycholecalciferol in healthy people.

Authors:  M McLaughlin; P R Raggatt; A Fairney; D J Brown; E Lester; M R Wills
Journal:  Lancet       Date:  1974-03-30       Impact factor: 79.321

6.  25-hydroxycholecalciferol. A biologically active metabolite of vitamin D3.

Authors:  J W Blunt; H F DeLuca; H K Schnoes
Journal:  Biochemistry       Date:  1968-10       Impact factor: 3.162

7.  The regulation of rat liver calciferol-25-hydroxylase.

Authors:  M H Bhattacharyya; H F DeLuca
Journal:  J Biol Chem       Date:  1973-05-10       Impact factor: 5.157

8.  25-Hydroxycholecalciferol-1-hydroxylase: a specific requirement for NADPH and a hemoprotein component in chick kidney mitochondria.

Authors:  J G Ghazarian; H F DeLuca
Journal:  Arch Biochem Biophys       Date:  1974-01       Impact factor: 4.013

9.  Biologically active metabolite of vitamin D3 from bone, liver, and blood serum.

Authors:  J Lund; H F DeLuca
Journal:  J Lipid Res       Date:  1966-11       Impact factor: 5.922

10.  Actinomycin D Inhibition of Vitamin D Action.

Authors:  J E Zull; E Czarnowska-Misztal; H F Deluca
Journal:  Science       Date:  1965-07-09       Impact factor: 47.728

  10 in total

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