BACKGROUND: Collagenous colitis and lymphocytic colitis present with a similar clinical picture. Whether these conditions are separate entities or whether they represent different pathological stages of the same condition is an unresolved issue. PATIENT: This is a case of collagenous colitis following a fulminant course in which a colectomy was necessary. In the operative specimen the thickened collagen plate, which had been present only two weeks preoperatively had been lost and the pathology was of a lymphocytic colitis. Six months postoperatively this patient developed a CREST syndrome and primary biliary cirrhosis. CONCLUSIONS: This case shows the lability of the collagen plate and the common ground between collagenous and lymphocytic colitis, and presents evidence that these two conditions are different manifestations of the same disease. It also describes for the first time an association between collagenous colitis and CREST syndrome and primary biliary cirrhosis.
BACKGROUND:Collagenous colitis and lymphocytic colitis present with a similar clinical picture. Whether these conditions are separate entities or whether they represent different pathological stages of the same condition is an unresolved issue. PATIENT: This is a case of collagenous colitis following a fulminant course in which a colectomy was necessary. In the operative specimen the thickened collagen plate, which had been present only two weeks preoperatively had been lost and the pathology was of a lymphocytic colitis. Six months postoperatively this patient developed a CREST syndrome and primary biliary cirrhosis. CONCLUSIONS: This case shows the lability of the collagen plate and the common ground between collagenous and lymphocytic colitis, and presents evidence that these two conditions are different manifestations of the same disease. It also describes for the first time an association between collagenous colitis and CREST syndrome and primary biliary cirrhosis.
Authors: F M Giardiello; A J Lazenby; T M Bayless; E J Levine; W B Bias; P W Ladenson; D F Hutcheon; N L Derevjanik; J H Yardley Journal: Dig Dis Sci Date: 1989-11 Impact factor: 3.199
Authors: Zsolt Barta; Gabriella Mekkel; István Csípo; László Tóth; Szabolcs Szakáll; Gábor-G Szabó; Gyula Bakó; Gyula Szegedi; Margit Zeher Journal: World J Gastroenterol Date: 2005-03-07 Impact factor: 5.742
Authors: F Baert; K Wouters; G D'Haens; P Hoang; S Naegels; F D'Heygere; J Holvoet; E Louis; M Devos; K Geboes Journal: Gut Date: 1999-09 Impact factor: 23.059
Authors: U Günther; D Schuppan; M Bauer; H Matthes; A Stallmach; A Schmitt-Gräff; E O Riecken; H Herbst Journal: Am J Pathol Date: 1999-08 Impact factor: 4.307