Literature DB >> 8706845

N-(2-ferrocene-ethyl)maleimide: a new electroactive sulphydryl-specific reagent for cysteine-containing peptides and proteins.

K Di Gleria1, H A Hill, L L Wong.   

Abstract

We report the synthesis and application of a specific electroactive label, N-(2-ferrocene-ethyl)maleimide, which provides new redox properties to organic compounds and proteins possessing sulphydryl groups. Its reaction conditions with the cysteine-containing peptide, glutathione, and a terminal monooxygenase enzyme, cytochrome P450cam are presented. The labelled peptide and enzyme acquired reversible electrochemical properties due to the attached ferrocene moiety.

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Year:  1996        PMID： 8706845     DOI： 10.1016/0014-5793(96)00648-5

Source DB:  PubMed          Journal:  FEBS Lett        ISSN： 0014-5793            Impact factor:   4.124


  6 in total

1.  DNA surface hybridization regimes.

Authors:  Ping Gong; Rastislav Levicky
Journal:  Proc Natl Acad Sci U S A       Date:  2008-04-01       Impact factor: 11.205

2.  Real-time, multiplexed electrochemical DNA detection using an active complementary metal-oxide-semiconductor biosensor array with integrated sensor electronics.

Authors:  Peter M Levine; Ping Gong; Rastislav Levicky; Kenneth L Shepard
Journal:  Biosens Bioelectron       Date:  2008-11-01       Impact factor: 10.618

3.  Interactions between redox complexes and semiconductor quantum dots coupled via a peptide bridge.

Authors:  Igor L Medintz; Thomas Pons; Scott A Trammell; Amy F Grimes; Doug S English; Juan B Blanco-Canosa; Philip E Dawson; Hedi Mattoussi
Journal:  J Am Chem Soc       Date:  2008-12-10       Impact factor: 15.419

4.  A comparison of five bioconjugatable ferrocenes for labeling of biomolecules.

Authors:  Dongbiao Ge; Rastislav Levicky
Journal:  Chem Commun (Camb)       Date:  2010-08-25       Impact factor: 6.222

5.  Synthesis of the unnatural amino acid N-N-(ferrocene-1-acetyl)-l-lysine: a novel organometallic nuclease.

Authors:  Amanda M Gellett; Paul W Huber; Pamela J Higgins
Journal:  J Organomet Chem       Date:  2008-09-01       Impact factor: 2.369

Review 6.  Electrochemistry of nonconjugated proteins and glycoproteins. Toward sensors for biomedicine and glycomics.

Authors:  Emil Paleček; Jan Tkáč; Martin Bartošík; Tomáš Bertók; Veronika Ostatná; Jan Paleček
Journal:  Chem Rev       Date:  2015-02-09       Impact factor: 60.622
  6 in total

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