Literature DB >> 8706239

Why have mortality rates for severe malnutrition remained so high?

C Schofield1, A Ashworth.   

Abstract

A review of the literature that has appeared over the past five decades indicates that the median case fatality from severe malnutrition has remained unchanged over this period and is typically 20-30%, with the highest levels (50-60%) being among those with oedematous malnutrition. A likely cause of this continuing high mortality is faulty case-management. A survey of treatment centres worldwide (n = 79) showed that for acutely ill children, inappropriate diets that are high in protein, energy and sodium and low in micronutrients are commonplace. Practices that could have fatal consequences, such as prescribing diuretics for oedema, were found to be widespread. Evidence of outmoded and conflicting teaching manuals also emerged. Since low mortality levels from malnutrition can be achieved using appropriate treatment regimens, updated treatment guidelines, which are practical and prescriptive rather than descriptive, need to be implemented as part of a comprehensive training programme.

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Year:  1996        PMID: 8706239      PMCID: PMC2486901     

Source DB:  PubMed          Journal:  Bull World Health Organ        ISSN: 0042-9686            Impact factor:   9.408


  41 in total

1.  An analysis of admissions to the Paediatric Division, Mulago Hospital in 1959.

Authors:  L K MUSOKE
Journal:  Arch Dis Child       Date:  1961-06       Impact factor: 3.791

2.  The results of treatment of kwashiorkor in Salisbury with high protein diets.

Authors:  W R CARR; M GELFAND
Journal:  Cent Afr J Med       Date:  1956-12

3.  High-energy feeding for protein-calorie malnutrition. Results in a rural hospital in Zambia.

Authors:  N M Hone; J K Fermor
Journal:  Trop Doct       Date:  1987-10       Impact factor: 0.731

4.  Dehydration syndrome in malnourished Iranian children.

Authors:  M Sadre; H Hedayat; M Gharib; Z Ghavam; G Donoso
Journal:  Am J Clin Nutr       Date:  1969-02       Impact factor: 7.045

5.  Protein-energy malnutrition in northern Sudan: clinical studies.

Authors:  J B Coulter; G I Suliman; M I Omer; S B Macfarlane; J B Moody; R G Hendrickse
Journal:  Eur J Clin Nutr       Date:  1988-09       Impact factor: 4.016

6.  Treatment of severe malnutrition.

Authors:  D Brewster; M Manary
Journal:  Lancet       Date:  1995-02-18       Impact factor: 79.321

7.  Treatment of severe child malnutrition in refugee camps.

Authors:  A Briend; M H Golden
Journal:  Eur J Clin Nutr       Date:  1993-10       Impact factor: 4.016

8.  Evaluation of Nutrition Rehabilitation Centre in Ile-Ife, Oyo State, Nigeria.

Authors:  E O Ojofeitimi; S O Teniola
Journal:  World Rev Nutr Diet       Date:  1980       Impact factor: 0.575

9.  Plant protein rehabilitation diets and iron supplementation of the protein-energy malnourished child.

Authors:  I F Smith; O Taiwo; M H Golden
Journal:  Eur J Clin Nutr       Date:  1989-11       Impact factor: 4.016

10.  Mortality risk factors in acute protein-energy malnutrition.

Authors:  S J Gillam
Journal:  Trop Doct       Date:  1989-04       Impact factor: 0.731

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  58 in total

Review 1.  Nutritional update: relevance to maternal and child health in East Africa.

Authors:  Maureen B Duggan
Journal:  Afr Health Sci       Date:  2003-12       Impact factor: 0.927

Review 2.  Management of the severely malnourished child: perspective from developing countries.

Authors:  Maharaj K Bhan; Nita Bhandari; Rajiv Bahl
Journal:  BMJ       Date:  2003-01-18

3.  Diagnostic performance of visible severe wasting for identifying severe acute malnutrition in children admitted to hospital in Kenya.

Authors:  Polycarp Mogeni; Hemed Twahir; Victor Bandika; Laura Mwalekwa; Johnstone Thitiri; Moses Ngari; Christopher Toromo; Kathryn Maitland; James A Berkley
Journal:  Bull World Health Organ       Date:  2011-10-19       Impact factor: 9.408

4.  Nutritional Rehabilitation of Children with Severe Acute Malnutrition.

Authors:  Rakesh Lodha
Journal:  Indian J Pediatr       Date:  2015-09-08       Impact factor: 1.967

Review 5.  Undernutrition, the acute phase response to infection, and its effects on micronutrient status indicators.

Authors:  Kara A Bresnahan; Sherry A Tanumihardjo
Journal:  Adv Nutr       Date:  2014-11-14       Impact factor: 8.701

6.  Predictors of mortality among hospitalized children with severe acute malnutrition: a prospective study from Uganda.

Authors:  Nicolette Nabukeera-Barungi; Benedikte Grenov; Betty Lanyero; Hanifa Namusoke; Ezekiel Mupere; Vibeke Brix Christensen; Kim F Michaelsen; Christian Mølgaard; Maren Johanne Rytter; Henrik Friis
Journal:  Pediatr Res       Date:  2018-05-23       Impact factor: 3.756

Review 7.  Malnutrition and health in developing countries.

Authors:  Olaf Müller; Michael Krawinkel
Journal:  CMAJ       Date:  2005-08-02       Impact factor: 8.262

8.  Quality of care in nutritional rehabilitation in HIV-endemic Malawi: caregiver perspectives.

Authors:  Pamela Fergusson; Kingsley Chikaphupha; Grace Bongololo; Ireen Makwiza; Lot Nyirenda; Jobiba Chinkhumba; Anisa Aslam; Sally Theobald
Journal:  Matern Child Nutr       Date:  2010-01       Impact factor: 3.092

9.  Protein and hematological evaluations of infant formulated from cooking banana fruits (Musa spp, ABB genome) and fermented bambara groundnut (Vigna subterranean L. Verdc) seeds.

Authors:  Oluwole Steve Ijarotimi
Journal:  Nutr Res Pract       Date:  2008-09-30       Impact factor: 1.926

10.  Phase II trial of isotonic fluid resuscitation in Kenyan children with severe malnutrition and hypovolaemia.

Authors:  Samuel O Akech; Japhet Karisa; Phellister Nakamya; Mwanamvua Boga; Kathryn Maitland
Journal:  BMC Pediatr       Date:  2010-10-06       Impact factor: 2.125

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