Literature DB >> 8704934

Simultaneous high-performance liquid chromatographic determination of caffeine and theophylline for routine drug monitoring in human plasma.

E Schreiber-Deturmeny1, B Bruguerolle.   

Abstract

An HPLC method for the simultaneous determination of both caffeine and theophylline in human plasma is described, using a reversed-phase chromatography column, heated by a thermostatic oven at 35 degrees C, with UV detection and isocratic elution. The linearity and reproducibility of the method are verified. For the two drugs, the limit of detection is 0.1 microgram ml-1. This analytical method is rapid and reliable and allows routine controls of therapeutic levels of theophylline and caffeine, especially in premature infants where the volume of plasma samples is very small.

Entities:  

Mesh：

Substances：

Year:  1996        PMID： 8704934     DOI： 10.1016/0378-4347(95)00383-5

Source DB:  PubMed          Journal:  J Chromatogr B Biomed Appl        ISSN： 1572-6495


  12 in total

1.  Dipyridamole enhances ischaemia-induced reactive hyperaemia by increased adenosine receptor stimulation.

Authors:  P Meijer; C W Wouters; P H H van den Broek; G J Scheffer; N P Riksen; P Smits; G A Rongen
Journal:  Br J Pharmacol       Date:  2008-02-11       Impact factor: 8.739

2.  Improved resistance to ischemia and reperfusion, but impaired protection by ischemic preconditioning in patients with type 1 diabetes mellitus: a pilot study.

Authors:  Richard Engbersen; Niels P Riksen; Marc J Mol; Bert Bravenboer; Otto C Boerman; Patrick Meijer; Wim J G Oyen; Cees Tack; Gerard A Rongen; Paul Smits
Journal:  Cardiovasc Diabetol       Date:  2012-10-10       Impact factor: 9.951

3.  Dipyridamole augments the antiinflammatory response during human endotoxemia.

Authors:  Bart P Ramakers; Niels P Riksen; Thijmen H Stal; Suzanne Heemskerk; Petra van den Broek; Wilbert H M Peters; Johannes G van der Hoeven; Paul Smits; Peter Pickkers
Journal:  Crit Care       Date:  2011-11-30       Impact factor: 9.097

4.  Impact of metformin on endothelial ischemia-reperfusion injury in humans in vivo: a prospective randomized open, blinded-endpoint study.

Authors:  Saloua El Messaoudi; Tim H Schreuder; Roel D Kengen; Gerard A Rongen; Petra H van den Broek; Dick H J Thijssen; Niels P Riksen
Journal:  PLoS One       Date:  2014-04-22       Impact factor: 3.240

5.  The effect of eplerenone on adenosine formation in humans in vivo: a double-blinded randomised controlled study.

Authors:  T N A van den Berg; Jaap Deinum; Albert Bilos; A Rogier T Donders; Gerard A Rongen; Niels P Riksen
Journal:  PLoS One       Date:  2014-10-30       Impact factor: 3.240

6.  Tea-induced improvement of endothelial function in humans: No role for epigallocatechin gallate (EGCG).

Authors:  Mario Lorenz; Franziska Rauhut; Christine Hofer; Stefanie Gwosc; Eda Müller; Damaris Praeger; Benno F Zimmermann; Klaus-Dieter Wernecke; Gert Baumann; Karl Stangl; Verena Stangl
Journal:  Sci Rep       Date:  2017-05-23       Impact factor: 4.379

7.  Hydrogel-Forming Microneedle Arrays for Enhanced Transdermal Drug Delivery.

Authors:  Ryan F Donnelly; Thakur Raghu Raj Singh; Martin J Garland; Katarzyna Migalska; Rita Majithiya; Cian M McCrudden; Prashant Laxman Kole; Tuan Mazlelaa Tuan Mahmood; Helen O McCarthy; A David Woolfson
Journal:  Adv Funct Mater       Date:  2012-07-09       Impact factor: 18.808

8.  Pharmacokinetics of Caffeine following a Single Administration of Coffee Enema versus Oral Coffee Consumption in Healthy Male Subjects.

Authors:  Supanimit Teekachunhatean; Nisanuch Tosri; Noppamas Rojanasthien; Somdet Srichairatanakool; Chaichan Sangdee
Journal:  ISRN Pharmacol       Date:  2013-03-04

9.  Ticagrelor Does Not Inhibit Adenosine Transport at Relevant Concentrations: A Randomized Cross-Over Study in Healthy Subjects In Vivo.

Authors:  T N A van den Berg; S El Messaoudi; G A Rongen; P H H van den Broek; A Bilos; A R T Donders; M E Gomes; N P Riksen
Journal:  PLoS One       Date:  2015-10-28       Impact factor: 3.240

10.  Plasma levels of the cardiovascular protective endogenous nucleoside adenosine are reduced in patients with primary aldosteronism without affecting ischaemia-reperfusion injury: A prospective case-control study.

Authors:  T N A Daniëlle van den Berg; Dick H J Thijssen; Anke C C M van Mil; Petra H van den Broek; Gerard A Rongen; Houshang Monajemi; Jaap Deinum; Niels P Riksen
Journal:  Eur J Clin Invest       Date:  2019-11-25       Impact factor: 4.686
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.