Literature DB >> 8704823

[Evaluation of the time response of a single dose administration of fenticonazole nitrate].

J Balaïsch.   

Abstract

174 women with vaginal candidosis confirmed by direct microscopic examination were treated with a single intravaginal fenticonazole nitrate capsule. One third received a second intravaginal capsule three days later. Fenticonazole nitrate cream was also applied daily on the vulvar area in 94.2% of cases. Efficacy was excellent. After one week improvement and complete healing rates were 88% and 80%, respectively. On the second day of treatment pruritus and burning abated in 78% and 85% of women. Mycologic cure demonstrated by microscopic examination was obtained in 92% of cases. Treatment acceptance and tolerance were rated good or excellent by 98% and 92% of patients. Absence of abnormal vaginal discharge due to vaginal capsule was considered as an advantage by women. Results of this trial performed on a large number of patients confirm that product efficacy is fast.

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Year:  1996        PMID: 8704823

Source DB:  PubMed          Journal:  Contracept Fertil Sex        ISSN: 1165-1083


  1 in total

Review 1.  Topical fenticonazole in dermatology and gynaecology: current role in therapy.

Authors:  Stefano Veraldi; Rodolfo Milani
Journal:  Drugs       Date:  2008       Impact factor: 9.546

  1 in total

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