Literature DB >> 870336

Effects of tranylcypromine and pargyline on brain tryptamine.

B Tabakoff, F Moses, S R Philips, A A Boulton.   

Abstract

Tranylcypromine produces behavioral excitation while pargyline produces depression. Tranylcypromine increased brain tryptophan which led to an accumulation of tryptamine. The levels of tryptamine after tranylcypromine were found to be 3 times those found after pargyline.

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Year:  1977        PMID： 870336     DOI： 10.1007/bf02002839

Source DB:  PubMed          Journal:  Experientia        ISSN： 0014-4754


  18 in total

1.  POTENTIATION OF MONOAMINE-OXIDASE INHIBITORS BY TRYPTOPHAN.

Authors:  C M PARE
Journal:  Lancet       Date:  1963-09-07       Impact factor: 79.321

2.  Relationship of brain monoamine and locomotor activity in rats.

Authors:  A Foldes; E Costa
Journal:  Biochem Pharmacol       Date:  1975-09-01       Impact factor: 5.858

3.  Tryptamines and some other substances affecting waking and sleep in fowls.

Authors:  E Marley; G Nistiò
Journal:  Br J Pharmacol       Date:  1975-02       Impact factor: 8.739

4.  Biosynthesis and excretion of meta and para tyramine in the rat.

Authors:  A A Boulton; L E Dyck
Journal:  Life Sci       Date:  1974-06-16       Impact factor: 5.037

5.  Effect of drugs on the tryptamine content of rat tissues.

Authors:  J M Saavedra; J Axelrod
Journal:  J Pharmacol Exp Ther       Date:  1973-06       Impact factor: 4.030

6.  Identification and distribution of tryptamine in the rat.

Authors:  S R Philips; D A Durden; A A Boulton
Journal:  Can J Biochem       Date:  1974-06

7.  Relationship between the action of monoamine oxidase inhibitors on the noradrenaline uptake system and their antidepressant efficacy.

Authors:  E D Hendley; S H Snyder
Journal:  Nature       Date:  1968-12-28       Impact factor: 49.962

8.  An assay procedure for tryptamine in brain and spinal cord using its (3H)dansyl derivative.

Authors:  S R Snodgrass; A S Horn
Journal:  J Neurochem       Date:  1973-09       Impact factor: 5.372

9.  Studies in vivo on the relationship between brain tryptophan, brain 5-HT synthesis and hyperactivity in rats treated with a monoamine oxidase inhibitor and L-tryptophan.

Authors:  D G Grahame-Smith
Journal:  J Neurochem       Date:  1971-06       Impact factor: 5.372

10.  The effect of L-tryptophan on spinal cord C-fiber reflexes.

Authors:  J A Bell; W R Martin; J W Sloan; W F Buchwald
Journal:  J Pharmacol Exp Ther       Date:  1976-02       Impact factor: 4.030
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  3 in total

1.  Effects of tranylcypromine on the concentration of some trace amines in the diencephalon and hippocampus of the rat.

Authors:  S R Philips; G B Baker; H R McKim
Journal:  Experientia       Date:  1980-02-15

2.  Effect of nonselective and selective inhibitors of monoamine oxidases A and B on pethidine toxicity in mice.

Authors:  R Boden; R Botting; P Coulson; G Spanswick
Journal:  Br J Pharmacol       Date:  1984-05       Impact factor: 8.739

3.  The trace amine theory of spontaneous hypertension as induced by classic monoamine oxidase inhibitors.

Authors:  Vincent Van den Eynde
Journal:  J Neural Transm (Vienna)       Date:  2021-08-09       Impact factor: 3.575
  3 in total

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