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Literature DB >> 870335

Calcium and the contractile response to prostaglandin in the smooth muscle of guinea-pig stomach.

Abstract

In the longitudinal smooth muscle of guinea-pig stomach, verapamil (10(-5) M) which showed marked suppression of high K-induced contractures, did not suppress the contractile response to PGE1 (1.5 X 10(-9) to 10(-6) M) markedly. These results suggest that the contractile mechanism of PGE1 in guinea-pig stomach may mainly depend on a release of bound Ca in the cell and partly depend on a Ca influx from the extracellular origin.

Entities: Chemical Disease Species

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Year: 1977 PMID： 870335 DOI： 10.1007/bf02002836

Source DB: PubMed Journal: Experientia ISSN： 0014-4754

13 in total

1. Spike-free activation mechanism in smooth muscle of guinea pig stomach.

Authors: K Golenhofen; N Wegner
Journal: Pflugers Arch Date: 1975 Impact factor: 3.657

2. Effect of isoproterenol and D-600 on calcium movements in rat myometrium.

Authors: E A Kroeger; J M Marshall; C P Bianchi
Journal: J Pharmacol Exp Ther Date: 1975-05 Impact factor: 4.030

Review 3. Excitation-contraction coupling in vertebrate smooth muscle: correlation of ultrastructure with function.

Authors: A P Somlyo
Journal: Physiologist Date: 1972-11

4. The action of lanthanum and D600 on the calcium exchange in the smooth muscle cells of the guinea-pig Taenia coli.

Authors: C J Mayer; C van Breemen; T Casteels
Journal: Pflugers Arch Date: 1972 Impact factor: 3.657

5. [Relationship between stimulating action of prostaglandin E1 and calcium on the gastrointestinal smooth muscle from the guinea-pig].

Authors: M Akanuma
Journal: Sapporo Igaku Zasshi Date: 1970 Jul-Aug

10. [Uterus relaxation by highly potent Ca plus,plus-antagonistic inhibitors of electro-mechanical coupling such as Isoptin (verapamil, iproveratril), compound D 600 and Segontin (prenylamine). Experiments on the isolated virgin rat uterus].

Authors: A Fleckenstein; G Grün; H Tritthart; K Byon
Journal: Klin Wochenschr Date: 1971-01

1 in total

1. Involvement of calcium channels in the contractile activity of neurotensin but not acetylcholine: studies with calcium channel blockers and Bay K 8644 on the rat fundus.

Authors: M V Donoso; J P Huidobro-Toro; A Kullak
Journal: Br J Pharmacol Date: 1986-08 Impact factor: 8.739

1 in total

Calcium and the contractile response to prostaglandin in the smooth muscle of guinea-pig stomach.

1. Spike-free activation mechanism in smooth muscle of guinea pig stomach.

2. Effect of isoproterenol and D-600 on calcium movements in rat myometrium.

Review 3. Excitation-contraction coupling in vertebrate smooth muscle: correlation of ultrastructure with function.

4. The action of lanthanum and D600 on the calcium exchange in the smooth muscle cells of the guinea-pig Taenia coli.

5. [Relationship between stimulating action of prostaglandin E1 and calcium on the gastrointestinal smooth muscle from the guinea-pig].

6. Subcellular myocardial effects of verapamil and D600: comparison with propranolol.

7. Localization of contractile-dependent Ca: comparison of Mn and verapamil in cardiac and skeletal muslce.

8. [Studies on the stimulating action of prostaglandin E on the intestinal smooth muscle].

9. Electrical and mechanical properties of longitudinal and circular muscles of the guinea-pig ileum.

10. [Uterus relaxation by highly potent Ca plus,plus-antagonistic inhibitors of electro-mechanical coupling such as Isoptin (verapamil, iproveratril), compound D 600 and Segontin (prenylamine). Experiments on the isolated virgin rat uterus].

1. Involvement of calcium channels in the contractile activity of neurotensin but not acetylcholine: studies with calcium channel blockers and Bay K 8644 on the rat fundus.