Literature DB >> 870334

The effect of vinblastin and vincristin on single nerve fibres.

D Mitolo-Chieppa.   

Abstract

The perfusion of the node of Ranvier with vinblastin or vincristin reduces the amplitude of the action potential within a few seconds. Vincristins is 10fold more active than vinblastin. Upon withdrawal, the effect is promptly reversible and its is antagonized by acetylcholine.

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Year:  1977        PMID： 870334     DOI： 10.1007/bf02002830

Source DB:  PubMed          Journal:  Experientia        ISSN： 0014-4754


  3 in total

1.  Is the resting potential of Ranvier nodes a potassium potential?

Authors:  R STAEMPFLI
Journal:  Ann N Y Acad Sci       Date:  1959-08-28       Impact factor: 5.691

2.  Vincristine neuropathy. Clinical and electrophysiological observations.

Authors:  E B Casey; A M Jellife; P M Le Quesne; Y L Millett
Journal:  Brain       Date:  1973       Impact factor: 13.501

3.  Neurofibrillary degeneration induced by vincristine therapy.

Authors:  M L Shelanski; H Wiśniewski
Journal:  Arch Neurol       Date:  1969-02
  3 in total
  1 in total

1.  Are axoplasmic microtubules necessary for membrane excitation?

Authors:  S Terakawa; T Nakayama
Journal:  J Membr Biol       Date:  1985       Impact factor: 1.843
  1 in total

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