Literature DB >> 8699181

Diterpenoid alkaloids from Delphinium davisii.

A Ulubelen1, H K Desai, S K Srivastava, B P Hart, J C Park, B S Joshi, S W Pelletier, A H Meriçli, F Meriçli, R Ilarslan.   

Abstract

Three new hetisane-type diterpenoid alkaloids, davisinol (6), 18-benzoyldavisinol (7), and Davisin (9) have been isolated from Delphinium davisii Munz. and their structures established by detailed spectroscopic studies. Accurate 1H- and 13C-NMR assignments have been made for kobusine (8), a related hetisane-type alkaloid, and karakoline (5), a norditerpenoid alkaloid. The known norditerpenoid alkaloids 14-acetylperegrine (4), 6-deacetylperegrine (3), and karakoline (5) and the diterpenoid alkaloids hetisine and hetisinone were also isolated.

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Year:  1996        PMID： 8699181     DOI： 10.1021/np960215f

Source DB:  PubMed          Journal:  J Nat Prod        ISSN： 0163-3864            Impact factor:   4.050


  5 in total

1.  A Benzyne Insertion Approach to Hetisine-Type Diterpenoid Alkaloids: Synthesis of Cossonidine (Davisine).

Authors:  Kevin G M Kou; Jason J Pflueger; Toshihiro Kiho; Louis C Morrill; Ethan L Fisher; Kyle Clagg; Terry P Lebold; Jessica K Kisunzu; Richmond Sarpong
Journal:  J Am Chem Soc       Date:  2018-06-19       Impact factor: 15.419

2.  Enantioselective approach to the hetisine alkaloids. Synthesis of the 3-methyl-1-aza-tricyclo[5.2.1.0(3,8)]decane core via intramolecular dipolar cycloaddition.

Authors:  Kevin M Peese; David Y Gin
Journal:  Org Lett       Date:  2005-07-21       Impact factor: 6.005

Review 3.  Chemistry and biological activities of hetisine-type diterpenoid alkaloids.

Authors:  Tianpeng Yin; Huixia Zhang; Wei Zhang; Zhihong Jiang
Journal:  RSC Adv       Date:  2021-11-08       Impact factor: 4.036

4.  A unified approach to ent-atisane diterpenes and related alkaloids: synthesis of (-)-methyl atisenoate, (-)-isoatisine, and the hetidine skeleton.

Authors:  Emily C Cherney; Justin M Lopchuk; Jason C Green; Phil S Baran
Journal:  J Am Chem Soc       Date:  2014-08-29       Impact factor: 15.419

5.  Structurally diverse diterpenoid alkaloids from the lateral roots of Aconitum carmichaelii Debx. and their anti-tumor activities based on in vitro systematic evaluation and network pharmacology analysis.

Authors:  Yang Yu; Shifei Wu; Jianqing Zhang; Jiayuan Li; Changliang Yao; Wenyong Wu; Yingying Wang; Hongjian Ji; Wenlong Wei; Min Gao; Yun Li; Shuai Yao; Yong Huang; Qirui Bi; Hua Qu; De-An Guo
Journal:  RSC Adv       Date:  2021-08-04       Impact factor: 4.036
  5 in total

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