Literature DB >> 8698022

Validation of reagent sticks in diagnosing urinary schistosomiasis in an urban setting.

D Mtasiwa1, C Mayombana, P Kilima, M Tanner.   

Abstract

In view of the established potential of reagent sticks for detecting haematuria, a pilot survey to validate their use in the diagnosis of urinary schistosomiasis in an urban setting was done at Kinyerezi primary school of Ilala district in Dar es salaam. From 404 pupils screened for the disease, 273 were positive for the eggs by microscopy (filtration method), giving a prevalence of 67.6% and 253 (92.6%) of those who were positive by microscopy were also positive for haematuria by reagent sticks. Out of 131 who had no disease, 113 (86.2%) were negative for haematuria by the reagent sticks. These findings indicate a high sensitivity and specificity of microhaematuria by the reagent sticks (92.6% and 86.2%) respectively. Taking microscopy as a standard test, macrohaematuria had a sensitivity and specificity of 40.6% and 90% respectively, for urinary schistosomiasis. The accuracy of microhaematuria by reagent sticks was 90% compared to macrohaematuria which was only 56.6%. The use of reagent sticks test in detecting microhaematuria is thus recommended as a valid and rapid diagnostic test for urinary schistosomiasis in the present setting.

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Year:  1996        PMID: 8698022

Source DB:  PubMed          Journal:  East Afr Med J        ISSN: 0012-835X


  5 in total

Review 1.  Circulating antigen tests and urine reagent strips for diagnosis of active schistosomiasis in endemic areas.

Authors:  Eleanor A Ochodo; Gowri Gopalakrishna; Bea Spek; Johannes B Reitsma; Lisette van Lieshout; Katja Polman; Poppy Lamberton; Patrick M M Bossuyt; Mariska M G Leeflang
Journal:  Cochrane Database Syst Rev       Date:  2015-03-11

Review 2.  Rapid mapping of schistosomiasis and other neglected tropical diseases in the context of integrated control programmes in Africa.

Authors:  S Brooker; N B Kabatereine; J O Gyapong; J R Stothard; J Utzinger
Journal:  Parasitology       Date:  2009-05-19       Impact factor: 3.234

Review 3.  A systematic literature review of schistosomiasis in urban and peri-urban settings.

Authors:  Katharina Klohe; Benjamin G Koudou; Alan Fenwick; Fiona Fleming; Amadou Garba; Anouk Gouvras; Emma M Harding-Esch; Stefanie Knopp; David Molyneux; Susan D'Souza; Jürg Utzinger; Penelope Vounatsou; Johannes Waltz; Yaobi Zhang; David Rollinson
Journal:  PLoS Negl Trop Dis       Date:  2021-02-25

4.  All that is blood is not schistosomiasis: experiences with reagent strip testing for urogenital schistosomiasis with special consideration to very-low prevalence settings.

Authors:  Stefanie J Krauth; Helena Greter; Katarina Stete; Jean T Coulibaly; Seïdinan I Traoré; Bongo N R Ngandolo; Louise Y Achi; Jakob Zinsstag; Eliézer K N'Goran; Jürg Utzinger
Journal:  Parasit Vectors       Date:  2015-11-10       Impact factor: 3.876

5.  Biosocial Determinants of Persistent Schistosomiasis among Schoolchildren in Tanzania despite Repeated Treatment.

Authors:  Rose E Donohue; Kijakazi O Mashoto; Godfrey M Mubyazi; Shirin Madon; Mwele N Malecela; Edwin Michael
Journal:  Trop Med Infect Dis       Date:  2017-12-04
  5 in total

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