Literature DB >> 8697817

Structures and chromosome locations of the human MEF2A gene and a pseudogene MEF2AP.

E Suzuki1, J Lowry, G Sonoda, J R Testa, K Walsh.   

Abstract

The MEF2 family of transcription factors control the expression of muscle-specific and mitogen-induced genes. Here we describe the isolation and structure of the human MEF2A gene. The protein coding region of MEF2A is divided by 10 introns. The 3' untranslated region (UTR) is 3.7 kb in length, and it contains a region that is highly homologous with a portion of the 3' UTR of Xenopus MEF2A. A partially processed pseudogene (MEF2AP) corresponding to MEF2A was also isolated and characterized. Human MEF2A was mapped by fluorescence in situ hybridization to chromosome 15q26, and MEF2AP was mapped to chromosome 1q24 --> q25.

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Year:  1996        PMID: 8697817     DOI: 10.1159/000134348

Source DB:  PubMed          Journal:  Cytogenet Cell Genet        ISSN: 0301-0171


  6 in total

1.  The MEF2A 3' untranslated region functions as a cis-acting translational repressor.

Authors:  B L Black; J Lu; E N Olson
Journal:  Mol Cell Biol       Date:  1997-05       Impact factor: 4.272

2.  Myocyte enhancer factor 2A is transcriptionally autoregulated.

Authors:  Bindu Ramachandran; Gengsheng Yu; Shiguang Li; Bangmin Zhu; Tod Gulick
Journal:  J Biol Chem       Date:  2007-12-10       Impact factor: 5.157

3.  Phosphorylation and alternative pre-mRNA splicing converge to regulate myocyte enhancer factor 2C activity.

Authors:  Bangmin Zhu; Tod Gulick
Journal:  Mol Cell Biol       Date:  2004-09       Impact factor: 4.272

4.  Identities of sequestered proteins in aggregates from cells with induced polyglutamine expression.

Authors:  S T Suhr; M C Senut; J P Whitelegge; K F Faull; D B Cuizon; F H Gage
Journal:  J Cell Biol       Date:  2001-04-16       Impact factor: 10.539

5.  Comparative genomic analysis of the arthropod muscle myosin heavy chain genes allows ancestral gene reconstruction and reveals a new type of 'partially' processed pseudogene.

Authors:  Florian Odronitz; Martin Kollmar
Journal:  BMC Mol Biol       Date:  2008-02-06       Impact factor: 2.946

6.  Isoform Specific Effects of Mef2C during Direct Cardiac Reprogramming.

Authors:  Li Wang; Peisen Huang; David Near; Karan Ravi; Yangxi Xu; Jiandong Liu; Li Qian
Journal:  Cells       Date:  2020-01-22       Impact factor: 6.600

  6 in total

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