Literature DB >> 8697663

Severe necroziting vasculitis in a patient with hepatitis C virus infection treated by interferon.

D Pateron1, O Fain, J Sehonnou, J C Trinchet, M Beaugrand.   

Abstract

We report a case of polyarteritis nodosa occurring in a patient with hepatitis C, ten days after the beginning of alpha-IFN therapy. There was no cryoglobulinemia. Serum HCV-RNA was detectable before INF therapy and disappeared during the vasculites. The patient received boli of methylprednisolone and the neurological and skin lesions regressed after 5 months. This observation could suggest a precocious response to alpha-INF and a relationship between INF and the occurrence of vasculites.

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Year:  1996        PMID： 8697663

Source DB:  PubMed          Journal:  Clin Exp Rheumatol        ISSN： 0392-856X            Impact factor:   4.473


  4 in total

1.  Human recombinant interferon alfa-2a for the treatment of Behçet's disease with sight threatening posterior or panuveitis.

Authors:  I Kötter; M Zierhut; A K Eckstein; R Vonthein; T Ness; I Günaydin; B Grimbacher; S Blaschke; W Meyer-Riemann; H H Peter; N Stübiger
Journal:  Br J Ophthalmol       Date:  2003-04       Impact factor: 4.638

2.  Treatment of ocular symptoms of Behçet's disease with interferon alpha 2a: a pilot study.

Authors:  I Kötter; A K Eckstein; N Stübiger; M Zierhut
Journal:  Br J Ophthalmol       Date:  1998-05       Impact factor: 4.638

Review 3.  Vasculitic complications of interferon-alpha treatment for chronic hepatitis C virus infection: case report and review of the literature.

Authors:  Wilke Beuthien; Hans-Ullrich Mellinghoff; Johannes von Kempis
Journal:  Clin Rheumatol       Date:  2005-06-30       Impact factor: 3.650

Review 4.  [Vasculitis associated with viral infections].

Authors:  Pascal Cohen; Loïc Guillevin
Journal:  Presse Med       Date:  2004-11-06       Impact factor: 1.228
  4 in total

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