| Literature DB >> 8697429 |
F Pedeutour1, J P Lacour, C Perrin, K Huffermann, M P Simon, N Ayraud, C Turc-Carel.
Abstract
We have identified a new dermatofibrosarcoma protuberans (DP) case with a t(17;22) (q22;q13) occurring in a child. The translocation was substantiated by the presence of one or two copies of the sole der(22)t(17;22). This rearrangement added to two normal chromosomes 17 and one or two chromosomes 22, resulted in trisomy 22cen-q13 and trisomy (or tetrasomy) 17q22-25. This observation confirms the specificity of the association of DP with the t(17;22) found together with extra copies of the der(22)t(17;22). It also points out a possible prevalence of translocation rather than rings in DP of the childhood disease.Entities:
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Year: 1996 PMID： 8697429 DOI： 10.1016/0165-4608(96)00089-1
Source DB: PubMed Journal: Cancer Genet Cytogenet ISSN： 0165-4608