Literature DB >> 8694794

Cyclic AMP inhibits expression of D-type cyclins and cdk4 and induces p27Kip1 in G-CSF-treated NFS-60 cells.

A C Ward1, X F Csar, B W Hoffmann, J A Hamilton.   

Abstract

The addition of cAMP inhibits G-CSF-mediated proliferation and suppresses pRB phosphorylation in NFS-60 cells. We show that the latter could be attributed to different effects of cAMP in these cells: (i) down-regulation of the levels of cyclins D2 and D3, and cdk4, and (ii) induction of the p27Kip1 inhibitor of cdk4.

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Year:  1996        PMID： 8694794     DOI： 10.1006/bbrc.1996.0976

Source DB:  PubMed          Journal:  Biochem Biophys Res Commun        ISSN： 0006-291X            Impact factor:   3.575


  8 in total

1.  Cyclic AMP inhibits the proliferation of thyroid carcinoma cell lines through regulation of CDK4 phosphorylation.

Authors:  Ana Sofia Rocha; Sabine Paternot; Katia Coulonval; Jacques E Dumont; Paula Soares; Pierre P Roger
Journal:  Mol Biol Cell       Date:  2008-09-17       Impact factor: 4.138

2.  Transforming growth factor beta(1) selectively inhibits the cyclic AMP-dependent proliferation of primary thyroid epithelial cells by preventing the association of cyclin D3-cdk4 with nuclear p27(kip1).

Authors:  F Depoortere; I Pirson; J Bartek; J E Dumont; P P Roger
Journal:  Mol Biol Cell       Date:  2000-03       Impact factor: 4.138

3.  Prostaglandin E2 mediates growth arrest in NFS-60 cells by down-regulating interleukin-6 receptor expression.

Authors:  Kumudika I de Silva; Asif N Daud; JiangPing Deng; Stephen B Jones; Richard L Gamelli; Ravi Shankar
Journal:  Biochem J       Date:  2003-02-15       Impact factor: 3.857

Review 4.  Hematopoietic cytokines for cardiac repair: mobilization of bone marrow cells and beyond.

Authors:  Santosh K Sanganalmath; Ahmed Abdel-Latif; Roberto Bolli; Yu-Ting Xuan; Buddhadeb Dawn
Journal:  Basic Res Cardiol       Date:  2011-05-04       Impact factor: 17.165

5.  A repressive role of enhancer of zeste homolog 2 in 11β-hydroxysteroid dehydrogenase type 2 expression in the human placenta.

Authors:  Rujuan Zuo; Xiaohui Liu; Wangsheng Wang; Wenjiao Li; Hao Ying; Kang Sun
Journal:  J Biol Chem       Date:  2017-03-16       Impact factor: 5.157

6.  cAMP suppresses p21ras and Raf-1 responses but not the Erk-1 response to granulocyte-colony-stimulating factor: possible Raf-1-independent activation of Erk-1.

Authors:  X F Csar; A C Ward; B W Hoffmann; G G Guy; J A Hamilton
Journal:  Biochem J       Date:  1997-02-15       Impact factor: 3.857

7.  Increased mitogen-activated protein kinase kinase/extracellularly regulated kinase activity in human endometrial stromal fibroblasts of women with endometriosis reduces 3',5'-cyclic adenosine 5'-monophosphate inhibition of cyclin D1.

Authors:  Michael C Velarde; Lusine Aghajanova; Camran R Nezhat; Linda C Giudice
Journal:  Endocrinology       Date:  2009-07-09       Impact factor: 4.736

8.  A requirement for cyclin D3-cyclin-dependent kinase (cdk)-4 assembly in the cyclic adenosine monophosphate-dependent proliferation of thyrocytes.

Authors:  F Depoortere; A Van Keymeulen; J Lukas; S Costagliola; J Bartkova; J E Dumont; J Bartek; P P Roger; S Dremier
Journal:  J Cell Biol       Date:  1998-03-23       Impact factor: 10.539
  8 in total

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