| Literature DB >> 8694204 |
A Black1, M R Sury, L Hemington, R Howard, A Mackersie, D J Hatch.
Abstract
The induction characteristics of sevoflurane and halothane were compared in 81 children aged 6 months to 6 years. The mean time taken to achieve loss of eyelash reflex was significantly shorter with sevoflurane than with halothane (sevoflurane, mean time (SD) 1 min 41 s (35 s), halothane, mean time (SD) 2 min 17 s (43 s), t = 4.11, p = < 0.01). The mean time taken to complete induction (to achieve steady spontaneous ventilation and small pupils with central gaze) was also shorter in children induced with sevoflurane (sevoflurane, mean time (SD) 3 min 58 s (1 min 8 s), halothane, mean time (SD) 4 min 50 s, (1 min 27 s), t = 2.29, p = 0.027). Effects on heart rate, blood pressure and oxygen saturation during induction were similar for both agents. There were no major complications during induction with either halothane or sevoflurane.Entities:
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Year: 1996 PMID： 8694204 DOI： 10.1111/j.1365-2044.1996.tb12559.x
Source DB: PubMed Journal: Anaesthesia ISSN： 0003-2409 Impact factor: 6.955