Literature DB >> 8691217

Polytolypin, a new antifungal triterpenoid from the coprophilous fungus Polytolypa hystricis.

W R Gamble1, J B Gloer, J A Scott, D Malloch.   

Abstract

Polytolypin [1], a new pentacyclic triterpenoid exhibiting antifungal and antibiotic activity, has been isolated from cultures of Polytolypa hystricis (JS189), a fungal colonist of porcupine dung. Two known compounds [2 and 3] were also isolated. Polytolypin was obtained by chromatographic fractionation of the EtOAc extract of P. hystricis liquid cultures, and the structure was assigned on the basis of 2D nmr and hrms data.

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Year:  1995        PMID: 8691217     DOI: 10.1021/np50126a034

Source DB:  PubMed          Journal:  J Nat Prod        ISSN: 0163-3864            Impact factor:   4.050


  3 in total

1.  Enfumafungin synthase represents a novel lineage of fungal triterpene cyclases.

Authors:  Eric Kuhnert; Yan Li; Nan Lan; Qun Yue; Li Chen; Russell J Cox; Zhiqiang An; Kenichi Yokoyama; Gerald F Bills
Journal:  Environ Microbiol       Date:  2018-09-13       Impact factor: 5.491

2.  Genome analysis reveals evolutionary mechanisms of adaptation in systemic dimorphic fungi.

Authors:  José F Muñoz; Juan G McEwen; Oliver K Clay; Christina A Cuomo
Journal:  Sci Rep       Date:  2018-03-14       Impact factor: 4.379

3.  Secondary Metabolites with Cytotoxic Activities from Streptomyces sp. BM-8 Isolated from the Feces of Equusquagga.

Authors:  Shengsheng Lu; Jianan Hu; Xi Xie; Runhong Zhou; Fangfang Li; Ruifeng Huang; Jian He
Journal:  Molecules       Date:  2021-12-13       Impact factor: 4.411

  3 in total

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