Literature DB >> 8691212

Bruceanols G and H cytotoxic quassinoids from Brucea antidysenterica.

K Imamura1, N Fukamiya, M Nakamura, M Okano, K Tagahara, K H Lee.   

Abstract

Two new quassinoids, bruceanols G [1] and H [4], were isolated from Brucea antidysenterica, and their structures were elucidated by spectral evidence and chemical transformation. Bruceanol G exhibited significant cytotoxicity against the COLO-205 and KB neoplastic cell lines with ED50 values of 0.44 and 0.55 microM, respectively.

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Year:  1995        PMID: 8691212     DOI: 10.1021/np50126a019

Source DB:  PubMed          Journal:  J Nat Prod        ISSN: 0163-3864            Impact factor:   4.050


  1 in total

Review 1.  Research of Brucea javanica against cancer.

Authors:  Zheng Yan; Gui-Fang Guo; Bei Zhang
Journal:  Chin J Integr Med       Date:  2016-04-04       Impact factor: 1.978

  1 in total

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