Literature DB >> 869108

Efficacy of various drugs for treatment of giardiasis. A comparative study.

G C Levi, C A de Avila, V Amato Neto.   

Abstract

A total of 172 patients with giardiasis were treated with four of the drugs most commonly used for this infection. All drugs were used in their usual posologic schedules. The cure rates achieved with furazolidone, nimorazole, metronidazole, and tinidazole were; respectively, 72%, 94%, 87%, and 97%, while in a control group given no medication stools of only 35% of the patients became negative. Side effects were of minor importance in patients treated with nimorazole and metronidazole, and were somewhat more frequent and severe in those treated with furazolidone. Tinidazole produced no side effects.

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Year:  1977        PMID: 869108     DOI: 10.4269/ajtmh.1977.26.564

Source DB:  PubMed          Journal:  Am J Trop Med Hyg        ISSN: 0002-9637            Impact factor:   2.345


  9 in total

Review 1.  WITHDRAWN: Drugs for treating giardiasis.

Authors:  J O M Zaat; T H G Mank; W J J Assendelft
Journal:  Cochrane Database Syst Rev       Date:  2007-07-18

Review 2.  Drugs for treating giardiasis.

Authors:  Carlos E Granados; Ludovic Reveiz; Luis G Uribe; Claudia P Criollo
Journal:  Cochrane Database Syst Rev       Date:  2012-12-12

Review 3.  Treatment of giardiasis.

Authors:  T B Gardner; D R Hill
Journal:  Clin Microbiol Rev       Date:  2001-01       Impact factor: 26.132

4.  Furazolidone versus ampicillin in the treatment of traveler's diarrhea.

Authors:  H L DuPont; C D Ericsson; E Galindo; L V Wood; D Morgan; J A Bitsura; J G Mendiola
Journal:  Antimicrob Agents Chemother       Date:  1984-08       Impact factor: 5.191

5.  Structure-activity relationships of pentamidine analogs against Giardia lamblia and correlation of antigiardial activity with DNA-binding affinity.

Authors:  C A Bell; M Cory; T A Fairley; J E Hall; R R Tidwell
Journal:  Antimicrob Agents Chemother       Date:  1991-06       Impact factor: 5.191

Review 6.  Human antiprotozoal therapy: past, present, and future.

Authors:  M Khaw; C B Panosian
Journal:  Clin Microbiol Rev       Date:  1995-07       Impact factor: 26.132

7.  Single-dose tinidazole for the treatment of giardiasis.

Authors:  P Speelman
Journal:  Antimicrob Agents Chemother       Date:  1985-02       Impact factor: 5.191

8.  In vitro susceptibilities of 25 Giardia lamblia isolates of human origin to six commonly used antiprotozoal agents.

Authors:  B Gordts; W Hemelhof; C Asselman; J P Butzler
Journal:  Antimicrob Agents Chemother       Date:  1985-09       Impact factor: 5.191

9.  The old and new therapeutic approaches to the treatment of giardiasis: where are we?

Authors:  Haendel G N O Busatti; Joseph F G Santos; Maria A Gomes
Journal:  Biologics       Date:  2009-07-13
  9 in total

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