Literature DB >> 8690311

Subchronic toxicity study of domoic acid in the rat.

J Truelove1, R Mueller, O Pulido, F Iverson.   

Abstract

Male and female Sprague-Dawley rats were dosed by gavage for 64 days with 0, 0.1 or 5 mg/kg/day domoic acid. Treated animals showed no clinical abnormalities. Terminal values in haematology and clinical chemistry did not reveal differences between treated and control groups. Findings in histopathology and immunohistochemistry were unremarkable. The 24-hr urinary excretion rate for domoic acid determined at three time points was approximately 1.8% of the dose and remained unchanged during the study.

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Year:  1996        PMID： 8690311     DOI： 10.1016/0278-6915(96)81814-x

Source DB:  PubMed          Journal:  Food Chem Toxicol        ISSN： 0278-6915            Impact factor:   6.023


  16 in total

Review 1.  Domoic acid as a developmental neurotoxin.

Authors:  Lucio G Costa; Gennaro Giordano; Elaine M Faustman
Journal:  Neurotoxicology       Date:  2010-05-13       Impact factor: 4.294

2.  Chronic low-level exposure to the common seafood toxin domoic acid causes cognitive deficits in mice.

Authors:  Kathi A Lefebvre; Preston S Kendrick; Warren Ladiges; Emma M Hiolski; Bridget E Ferriss; Donald R Smith; David J Marcinek
Journal:  Harmful Algae       Date:  2017-03-27       Impact factor: 4.273

3.  Sigma receptors [σRs]: biology in normal and diseased states.

Authors:  Colin G Rousseaux; Stephanie F Greene
Journal:  J Recept Signal Transduct Res       Date:  2015-06-09       Impact factor: 2.092

4.  Repeated low level domoic acid exposure increases CA1 VGluT1 levels, but not bouton density, VGluT2 or VGAT levels in the hippocampus of adult mice.

Authors:  Caitlin E Moyer; Emma M Hiolski; David J Marcinek; Kathi A Lefebvre; Donald R Smith; Yi Zuo
Journal:  Harmful Algae       Date:  2018-09-05       Impact factor: 4.273

5.  Acute and chronic dietary exposure to domoic acid in recreational harvesters: A survey of shellfish consumption behavior.

Authors:  Bridget E Ferriss; David J Marcinek; Daniel Ayres; Jerry Borchert; Kathi A Lefebvre
Journal:  Environ Int       Date:  2017-01-18       Impact factor: 9.621

6.  Toxic effects of domoic acid in the seabream Sparus aurata.

Authors:  Isabel Nogueira; Alexandre Lobo-da-Cunha; António Afonso; Socorro Rivera; Joana Azevedo; Rogério Monteiro; Rosa Cervantes; Ana Gago-Martinez; Vítor Vasconcelos
Journal:  Mar Drugs       Date:  2010-10-15       Impact factor: 5.118

7.  Low-level domoic acid protects mouse cerebellar granule neurons from acute neurotoxicity: role of glutathione.

Authors:  Gennaro Giordano; Terrance J Kavanagh; Elaine M Faustman; Collin C White; Lucio G Costa
Journal:  Toxicol Sci       Date:  2013-01-12       Impact factor: 4.849

8.  Novel symptomatology and changing epidemiology of domoic acid toxicosis in California sea lions (Zalophus californianus): an increasing risk to marine mammal health.

Authors:  T Goldstein; J A K Mazet; T S Zabka; G Langlois; K M Colegrove; M Silver; S Bargu; F Van Dolah; T Leighfield; P A Conrad; J Barakos; D C Williams; S Dennison; M Haulena; F M D Gulland
Journal:  Proc Biol Sci       Date:  2008-02-07       Impact factor: 5.349

9.  Toxicokinetics and Physiologically Based Pharmacokinetic Modeling of the Shellfish Toxin Domoic Acid in Nonhuman Primates.

Authors:  Jing Jing; Rebekah Petroff; Sara Shum; Brenda Crouthamel; Ariel R Topletz; Kimberly S Grant; Thomas M Burbacher; Nina Isoherranen
Journal:  Drug Metab Dispos       Date:  2017-11-17       Impact factor: 3.922

Review 10.  Domoic acid: neurobehavioral consequences of exposure to a prevalent marine biotoxin.

Authors:  Kimberly S Grant; Thomas M Burbacher; Elaine M Faustman; Lynn Gratttan
Journal:  Neurotoxicol Teratol       Date:  2009-09-30       Impact factor: 3.763
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