| Literature DB >> 8689512 |
K Nishimura1, M Higashino, T Hara, T Oka.
Abstract
A rare case of bladder cancer producing granulocyte colony-stimulating factor (G-CSF) is reported. A 63-year-old man with a progressive, grade 3 transitional cell bladder carcinoma, showed marked leukocytosis (maximum 181,800/mm3) and an elevated serum G-CSF to 131.7 pg/mL. After radical cystectomy and neoadjuvant chemotherapy, the tumor recurred locally. Immunohistochemical examination with monoclonal antibody specific for G-CSF revealed positive staining in the local recurrent tumor. To our knowledge, there have been only seven cases reported of bladder cancer producing G-CSF.Entities:
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Year: 1996 PMID： 8689512 DOI： 10.1111/j.1442-2042.1996.tb00502.x
Source DB: PubMed Journal: Int J Urol ISSN： 0919-8172 Impact factor: 3.369