Literature DB >> 8688458

Cloning and sequencing of cDNAs encoding the human sperm protein, Sp17.

I A Lea1, R T Richardson, E E Widgren, M G O'Rand.   

Abstract

In the present study we have cloned and sequenced two testis-specific cDNAs (1.3 kb and 1.6 kb) encoding a human sperm protein, designated HSp17. Each cDNA gave rise to identical protein sequences and differed only in the 5' untranslated region. The predicted amino-acid sequence revealed a protein of 17.5 kDa which exhibited a high degree of homology with both rabbit and mouse Sp17. Analysis of native and recombinant Sp17 by SDS-PAGE has shown the apparent molecular weight of the protein to be 24.5 kDa.

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Year:  1996        PMID： 8688458     DOI： 10.1016/0167-4781(96)00077-2

Source DB:  PubMed          Journal:  Biochim Biophys Acta        ISSN： 0006-3002


  9 in total

1.  Characterization of Sp17: a ubiquitous three domain protein that binds heparin.

Authors:  Y Wen; R T Richardson; E E Widgren; M G O'Rand
Journal:  Biochem J       Date:  2001-07-01       Impact factor: 3.857

Review 2.  Cancer/testis (CT) antigens, carcinogenesis and spermatogenesis.

Authors:  Yan-Ho Cheng; Elissa Wp Wong; C Yan Cheng
Journal:  Spermatogenesis       Date:  2011-07-01

3.  Anti-Sp17 monoclonal antibody with antibody-dependent cell-mediated cytotoxicity and complement-dependent cytotoxicity activities against human ovarian cancer cells.

Authors:  Jia-xi Song; Wang-li Cao; Fang-qiu Li; Li-ning Shi; Xuan Jia
Journal:  Med Oncol       Date:  2011-12-24       Impact factor: 3.064

4.  A fusion-protein approach enabling mammalian cell production of tumor targeting protein domains for therapeutic development.

Authors:  Jia Hu; Xiang Chen; Xuhua Zhang; Xiaopeng Yuan; Mingjuan Yang; Hui Dai; Wei Yang; Qinghua Zhou; Weihong Wen; Qirui Wang; Weijun Qin; Aizhi Zhao
Journal:  Protein Sci       Date:  2018-04-14       Impact factor: 6.725

5.  Two genes encoding GH10 xylanases are essential for the virulence of the oomycete plant pathogen Phytophthora parasitica.

Authors:  Ming-Wei Lai; Ruey-Fen Liou
Journal:  Curr Genet       Date:  2018-02-22       Impact factor: 3.886

6.  Sperm protein 17 is highly expressed in endometrial and cervical cancers.

Authors:  Fang-Qiu Li; Qun Liu; Yan-Ling Han; Bo Wu; Hong-Lin Yin
Journal:  BMC Cancer       Date:  2010-08-16       Impact factor: 4.430

7.  Sperm protein 17 is expressed in the sperm fibrous sheath.

Authors:  Maurizio Chiriva-Internati; Nicoletta Gagliano; Elena Donetti; Francesco Costa; Fabio Grizzi; Barbara Franceschini; Elena Albani; Paolo E Levi-Setti; Magda Gioia; Marjorie Jenkins; Everardo Cobos; W Martin Kast
Journal:  J Transl Med       Date:  2009-07-15       Impact factor: 5.531

8.  Association of sperm protein 17 with A-kinase anchoring protein 3 in flagella.

Authors:  Isabel A Lea; Esther E Widgren; Michael G O'Rand
Journal:  Reprod Biol Endocrinol       Date:  2004-07-16       Impact factor: 5.211

Review 9.  Sperm specific proteins-potential candidate molecules for fertility control.

Authors:  Anil Suri
Journal:  Reprod Biol Endocrinol       Date:  2004-03-10       Impact factor: 5.211
  9 in total

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