Literature DB >> 8688224

[Results of postoperative cervical node irradiation in carcinoma of the pharyngo-larynx. A study of the cooperative group of radiotherapists].

S Hoffstetter1, L Malissard, T D N'Guyen, X Panis, G M Jung, J M Bachaud, B Prevost, R Quint, G Chaplain, F Eschwège, P Rambert, F Fleury-Touzeau.   

Abstract

From 1981 to 1985, 428 patients presenting with an epidermoid carcinoma of the hypopharynx and/or larynx were treated with a curative intent by surgical resection and postoperative irradiation. Two-thirds of the tumours were T3 and 60% of patients presented with a clinical node involvement. The rates of local failure were 8%, 18% and 13%, respectively, for cancers of the larynx, of the piriform sinus and of the posterior wall; the rates of regional failure were 8%, 23% and 13%, respectively. There is no head and neck site with either a high or low risk of recurrence after resection, but the capsular rupture remains a factor of poor prognosis. The survival rate at 5 years of the whole series is 38%, for laryngeal localisation it reaches 62%. The risk of metastases is related to the node involvement and the interval between surgery and irradiation.

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Mesh:

Year:  1996        PMID: 8688224

Source DB:  PubMed          Journal:  Bull Cancer Radiother        ISSN: 0924-4212


  2 in total

1.  Expression TGM2 and BNIP3 have prognostic significance in laryngeal cancer patients receiving surgery and postoperative radiotherapy: a retrospective study.

Authors:  Ting Jin; Huan-Xin Lin; Hui Lin; Li-Bing Guo; Nan Ge; Xiu-Yu Cai; Rui Sun; Wen-Kuan Chen; Qiu-Li Li; Wei-Han Hu
Journal:  J Transl Med       Date:  2012-03-30       Impact factor: 5.531

2.  Treatment results and prognostic factors of patients undergoing postoperative radiotherapy for laryngeal squamous cell carcinoma.

Authors:  Ting Jin; Wei-Han Hu; Li-Bing Guo; Wen-Kuan Chen; Qiu-Li Li; Hui Lin; Xiu-Yu Cai; Nan Ge; Rui Sun; Si-Yi Bu; Xin Zhang; Meng-Yao Qiu; Wei Zhang; Su Luo; Yi-Xin Zhou
Journal:  Chin J Cancer       Date:  2011-07
  2 in total

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