| Literature DB >> 8688224 |
S Hoffstetter1, L Malissard, T D N'Guyen, X Panis, G M Jung, J M Bachaud, B Prevost, R Quint, G Chaplain, F Eschwège, P Rambert, F Fleury-Touzeau.
Abstract
From 1981 to 1985, 428 patients presenting with an epidermoid carcinoma of the hypopharynx and/or larynx were treated with a curative intent by surgical resection and postoperative irradiation. Two-thirds of the tumours were T3 and 60% of patients presented with a clinical node involvement. The rates of local failure were 8%, 18% and 13%, respectively, for cancers of the larynx, of the piriform sinus and of the posterior wall; the rates of regional failure were 8%, 23% and 13%, respectively. There is no head and neck site with either a high or low risk of recurrence after resection, but the capsular rupture remains a factor of poor prognosis. The survival rate at 5 years of the whole series is 38%, for laryngeal localisation it reaches 62%. The risk of metastases is related to the node involvement and the interval between surgery and irradiation.Entities:
Mesh:
Year: 1996 PMID: 8688224
Source DB: PubMed Journal: Bull Cancer Radiother ISSN: 0924-4212