Literature DB >> 868717

Oral hyposensitization of children with pollinosis or house-dust asthma.

F Wortmann.   

Abstract

25 years of experience have proven oral hyposensitization to be an effective and safe method for specific treatment of respiratory allergies in children up to the age of 10-12 years. For pollinosis aqueous extracts or pollen powder are used. Results after at least two cures are comparable to those observed after subcutaneous hyposensitization. In house-dust asthma oral hyposensitization is performed either with commercially available extracts or with extracts prepared from the patient's own house-dust. The way to collect such dust samples, their use in testing and the preparation of extracts from it are described. Long-term results with oral hyposensitization of children with house-dust asthma are good.

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Year:  1977        PMID: 868717

Source DB:  PubMed          Journal:  Allergol Immunopathol (Madr)        ISSN: 0301-0546            Impact factor:   1.667


  5 in total

1.  Cholera toxin B subunit: an efficient transmucosal carrier-delivery system for induction of peripheral immunological tolerance.

Authors:  J B Sun; J Holmgren; C Czerkinsky
Journal:  Proc Natl Acad Sci U S A       Date:  1994-11-08       Impact factor: 11.205

2.  A cholera toxoid-insulin conjugate as an oral vaccine against spontaneous autoimmune diabetes.

Authors:  I Bergerot; C Ploix; J Petersen; V Moulin; C Rask; N Fabien; M Lindblad; A Mayer; C Czerkinsky; J Holmgren; C Thivolet
Journal:  Proc Natl Acad Sci U S A       Date:  1997-04-29       Impact factor: 11.205

3.  The kinetics of oral hyposensitization to a protein antigen are determined by immune status and the timing, dose and frequency of antigen administration.

Authors:  H J Peng; M W Turner; S Strobel
Journal:  Immunology       Date:  1989-07       Impact factor: 7.397

4.  Clinical and immunological response to oral and subcutaneous immunotherapy with grass pollen extracts. A prospective study.

Authors:  W Rebien; E Puttonen; H J Maasch; E Stix; U Wahn
Journal:  Eur J Pediatr       Date:  1982-07       Impact factor: 3.183

Review 5.  Mucosal immunity and tolerance: relevance to vaccine development.

Authors:  C Czerkinsky; F Anjuere; J R McGhee; A George-Chandy; J Holmgren; M P Kieny; K Fujiyashi; J F Mestecky; V Pierrefite-Carle; C Rask; J B Sun
Journal:  Immunol Rev       Date:  1999-08       Impact factor: 12.988

  5 in total

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