Literature DB >> 8686299

Role of nitric oxide in progression and regression of atherosclerosis.

J P Cooke1.   

Abstract

Endothelium-derived nitric oxide is a potent endogenous vasodilator that is derived from the metabolism of L-arginine. This endothelial factor inhibits circulating blood elements from interacting with the vessel wall. Platelet adherence and aggregation as well as monocyte adherence and infiltration are opposed by this paracrine substance. By virtue of these characteristics, endothelium-derived nitric oxide inhibits atherogenesis in animal models and may even induce regression.

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Year:  1996        PMID： 8686299      PMCID： PMC1303540     

Source DB:  PubMed          Journal:  West J Med        ISSN： 0093-0415


  46 in total

1.  Inhibitory role of the endothelium in the response of isolated coronary arteries to platelets.

Authors:  R A Cohen; J T Shepherd; P M Vanhoutte
Journal:  Science       Date:  1983-07-15       Impact factor: 47.728

2.  Enhanced endothelial adhesiveness in hypercholesterolemia is attenuated by L-arginine.

Authors:  P S Tsao; L M McEvoy; H Drexler; E C Butcher; J P Cooke
Journal:  Circulation       Date:  1994-05       Impact factor: 29.690

3.  Nitric oxide decreases cytokine-induced endothelial activation. Nitric oxide selectively reduces endothelial expression of adhesion molecules and proinflammatory cytokines.

Authors:  R De Caterina; P Libby; H B Peng; V J Thannickal; T B Rajavashisth; M A Gimbrone; W S Shin; J K Liao
Journal:  J Clin Invest       Date:  1995-07       Impact factor: 14.808

4.  L-arginine improves endothelium-dependent vasorelaxation and reduces intimal hyperplasia after balloon angioplasty.

Authors:  W C Tarry; R G Makhoul
Journal:  Arterioscler Thromb       Date:  1994-06

5.  The obligatory role of endothelial cells in the relaxation of arterial smooth muscle by acetylcholine.

Authors:  R F Furchgott; J V Zawadzki
Journal:  Nature       Date:  1980-11-27       Impact factor: 49.962

6.  Endothelium-dependent relaxation of coronary arteries by noradrenaline and serotonin.

Authors:  T M Cocks; J A Angus
Journal:  Nature       Date:  1983 Oct 13-19       Impact factor: 49.962

7.  Inhibition of human platelet aggregation by S-nitrosothiols. Heme-dependent activation of soluble guanylate cyclase and stimulation of cyclic GMP accumulation.

Authors:  B T Mellion; L J Ignarro; C B Myers; E H Ohlstein; B A Ballot; A L Hyman; P J Kadowitz
Journal:  Mol Pharmacol       Date:  1983-05       Impact factor: 4.436

8.  Gene therapy inhibiting neointimal vascular lesion: in vivo transfer of endothelial cell nitric oxide synthase gene.

Authors:  H E von der Leyen; G H Gibbons; R Morishita; N P Lewis; L Zhang; M Nakajima; Y Kaneda; J P Cooke; V J Dzau
Journal:  Proc Natl Acad Sci U S A       Date:  1995-02-14       Impact factor: 11.205

9.  Heterogeneous behavior of the canine arterial and venous wall. Importance of the endothelium.

Authors:  J G De Mey; P M Vanhoutte
Journal:  Circ Res       Date:  1982-10       Impact factor: 17.367

10.  Nitric oxide inhibits macrophage-colony stimulating factor gene transcription in vascular endothelial cells.

Authors:  H B Peng; T B Rajavashisth; P Libby; J K Liao
Journal:  J Biol Chem       Date:  1995-07-14       Impact factor: 5.157
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  3 in total

1.  Association of endothelial nitric oxide synthase polymorphisms with coronary artery disease in Korean individuals with or without diabetes mellitus.

Authors:  Jeehyeon Bae; In Jai Kim; Seung Ho Hong; Jung Hoon Sung; Sang Wook Lim; Dong Hoon Cha; Yong Wook Cho; Doyeun Oh; Nam Keun Kim
Journal:  Exp Ther Med       Date:  2010-07-01       Impact factor: 2.447

2.  Effect of Enhanced External Counterpulsation and Cardiac Rehabilitation on Quality of Life, Plasma Nitric Oxide, Endothelin 1 and High Sensitive CRP in Patients With Coronary Artery Disease: A Pilot Study.

Authors:  Seyed Kazem Shakouri; Zeynab Razavi; Fariba Eslamian; Homayoun Sadeghi-Bazargani; Samad Ghaffari; Arash Babaei-Ghazani
Journal:  Ann Rehabil Med       Date:  2015-04-24

3.  Combined effects of cigarette smoking, alcohol drinking and eNOS Glu298Asp polymorphism on blood pressure in Chinese male hypertensive subjects.

Authors:  Zhe Hong; Liying Pan; Zhangqing Ma; Yue Zhu; Zongyuan Hong
Journal:  Tob Induc Dis       Date:  2019-08-02       Impact factor: 2.600
  3 in total

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