Literature DB >> 8686265

[Development and study of the properties of immunoglobulin against Ebola fever].

I V Borisevich, V V Mikhaĭlov, V P Krasnianskiĭ, V N Gradoboev, E V Lebedinskaia, N V Potryvaeva, G D Timan'kova.   

Abstract

Immunoglobulin to Ebola fever has been for the first time prepared from hyperimmune equine blood sera by alcohol fractionation after Cohn. Preclinical study of the physicochemical and immunobiological properties of immunoglobulin showed that it protects up to 100% Papio hamadryas infected intramuscularly at doses of 110 to 29 LD50 Ebola virus. Scheme for the use of Ebola immunoglobulin has been experimentally validated.

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Year:  1995        PMID: 8686265

Source DB:  PubMed          Journal:  Vopr Virusol        ISSN: 0507-4088


  12 in total

1.  Pre- and postexposure prophylaxis of Ebola virus infection in an animal model by passive transfer of a neutralizing human antibody.

Authors:  Paul W H I Parren; Tom W Geisbert; Toshiaki Maruyama; Peter B Jahrling; Dennis R Burton
Journal:  J Virol       Date:  2002-06       Impact factor: 5.103

2.  Postexposure antibody prophylaxis protects nonhuman primates from filovirus disease.

Authors:  John M Dye; Andrew S Herbert; Ana I Kuehne; James F Barth; Majidat A Muhammad; Samantha E Zak; Ramon A Ortiz; Laura I Prugar; William D Pratt
Journal:  Proc Natl Acad Sci U S A       Date:  2012-03-12       Impact factor: 11.205

3.  Ebolavirus glycoprotein structure and mechanism of entry.

Authors:  Jeffrey E Lee; Erica Ollmann Saphire
Journal:  Future Virol       Date:  2009       Impact factor: 1.831

4.  Delayed treatment of Ebola virus infection with plant-derived monoclonal antibodies provides protection in rhesus macaques.

Authors:  Gene Garrard Olinger; James Pettitt; Do Kim; Cara Working; Ognian Bohorov; Barry Bratcher; Ernie Hiatt; Steven D Hume; Ashley K Johnson; Josh Morton; Michael Pauly; Kevin J Whaley; Calli M Lear; Julia E Biggins; Corinne Scully; Lisa Hensley; Larry Zeitlin
Journal:  Proc Natl Acad Sci U S A       Date:  2012-10-15       Impact factor: 11.205

5.  Pathogenesis of Ebola hemorrhagic fever in cynomolgus macaques: evidence that dendritic cells are early and sustained targets of infection.

Authors:  Thomas W Geisbert; Lisa E Hensley; Tom Larsen; Howard A Young; Douglas S Reed; Joan B Geisbert; Dana P Scott; Elliott Kagan; Peter B Jahrling; Kelly J Davis
Journal:  Am J Pathol       Date:  2003-12       Impact factor: 4.307

6.  Disease modeling for Ebola and Marburg viruses.

Authors:  Dennis Bente; Jason Gren; James E Strong; Heinz Feldmann
Journal:  Dis Model Mech       Date:  2009 Jan-Feb       Impact factor: 5.758

Review 7.  Correlates of immunity to filovirus infection.

Authors:  Steven B Bradfute; Sina Bavari
Journal:  Viruses       Date:  2011-06-27       Impact factor: 5.048

8.  Neutralizing antibody fails to impact the course of Ebola virus infection in monkeys.

Authors:  Wendelien B Oswald; Thomas W Geisbert; Kelly J Davis; Joan B Geisbert; Nancy J Sullivan; Peter B Jahrling; Paul W H I Parren; Dennis R Burton
Journal:  PLoS Pathog       Date:  2007-01       Impact factor: 6.823

Review 9.  Filoviruses: One of These Things is (not) Like the Other.

Authors:  Scott M Anthony; Steven B Bradfute
Journal:  Viruses       Date:  2015-09-29       Impact factor: 5.048

Review 10.  Mouse models for filovirus infections.

Authors:  Steven B Bradfute; Kelly L Warfield; Mike Bray
Journal:  Viruses       Date:  2012-09-07       Impact factor: 5.048

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