Radiation therapy in Burkitt's lymphoma of the central nervous system.

Involvement of the central nervous system in patients with with Burkitt's lymphoma was treated by superfractionated irradiation. The primary effect in 20 patients is reported. In 3 of 5 patients with paraplegia, complete regression was achieved. Only one patient of 6 with cranial neuropathy and irradiated to the brain improved. In 8 patients with either cranial neuropathy or other neurologic symptoms of signs, the brain and spinal cord were irradiated. Three of these patients, with recurrences after previous intrathecal chemotherapy, responded with complete regression.