Literature DB >> 8684383

Core Assessment Program for Intracerebral Transplantation in Huntington's Disease (CAPIT-HD).

N Quinn1, R Brown, D Craufurd, S Goldman, J Hodges, K Kieburtz, O Lindvall, J MacMillan, R Roos.   

Abstract

Studies in Parkinson's disease using the Core Assessment Program for Intracerebral Transplantation (CAPIT) protocol have demonstrated that grafts of embryonic mesencephalic cells into striatum can survive, grow, and exert useful clinical effects. Attention in now being directed toward neural grafting in other conditions, such as Huntington's disease. As a precondition for grafting of embryonic striatal cells into diseased striatum in this complex motor and psychiatric disorder, not only is further basic research needed, but also a thorough and wide-ranging assessment protocol is essential. This article presents such a CAPIT-HD assessment protocol.

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Year:  1996        PMID： 8684383     DOI： 10.1002/mds.870110205

Source DB:  PubMed          Journal:  Mov Disord        ISSN： 0885-3185            Impact factor:   10.338


  21 in total

Review 1.  Aspects of PET imaging relevant to the assessment of striatal transplantation in Huntington's disease.

Authors:  L Besret; A L Kendall; S B Dunnett
Journal:  J Anat       Date:  2000-05       Impact factor: 2.610

2.  Unilateral transplantation of human primary fetal tissue in four patients with Huntington's disease: NEST-UK safety report ISRCTN no 36485475.

Authors:  A E Rosser; R A Barker; T Harrower; C Watts; M Farrington; A K Ho; R M Burnstein; D K Menon; J H Gillard; J Pickard; S B Dunnett
Journal:  J Neurol Neurosurg Psychiatry       Date:  2002-12       Impact factor: 10.154

3.  Huntington's Disease.

Authors: 
Journal:  Curr Treat Options Neurol       Date:  2000-05       Impact factor: 3.598

Review 4.  Neural transplantation in patients with Huntington's disease.

Authors:  Anne E Rosser; Stephen B Dunnett
Journal:  CNS Drugs       Date:  2003       Impact factor: 5.749

Review 5.  The design of clinical trials for cell transplantation into the central nervous system.

Authors:  Pierre Cesaro
Journal:  NeuroRx       Date:  2004-10

6.  A patient with Huntington's disease and long-surviving fetal neural transplants that developed mass lesions.

Authors:  C Dirk Keene; Rubens C Chang; James B Leverenz; Oleg Kopyov; Susan Perlman; Robert F Hevner; Donald E Born; Thomas D Bird; Thomas J Montine
Journal:  Acta Neuropathol       Date:  2008-12-05       Impact factor: 17.088

Review 7.  Cell therapy in Huntington's disease.

Authors:  Stephen B Dunnett; Anne E Rosser
Journal:  NeuroRx       Date:  2004-10

8.  Striatal metabolism and psychomotor speed as predictors of motor onset in Huntington's disease.

Authors:  Meike Herben-Dekker; Joost C H van Oostrom; Raymund A C Roos; Caroline K Jurgens; Marie-Noëlle W Witjes-Ané; Hubertus P H Kremer; Klaus L Leenders; Jacoba M Spikman
Journal:  J Neurol       Date:  2014-04-30       Impact factor: 4.849

9.  Recent advances in the management of choreas.

Authors:  Jean-Marc Burgunder
Journal:  Ther Adv Neurol Disord       Date:  2013-03       Impact factor: 6.570

10.  Cognitive changes in patients with Huntington's disease (HD) and asymptomatic carriers of the HD mutation--a longitudinal follow-up study.

Authors:  Jurgen Lemiere; Marleen Decruyenaere; Gery Evers-Kiebooms; Erik Vandenbussche; Rene Dom
Journal:  J Neurol       Date:  2004-08       Impact factor: 4.849
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