Literature DB >> 8682903

Relationships between serum free fatty acids and zinc, and attention deficit hyperactivity disorder: a research note.

M Bekaroğlu1, Y Aslan, Y Gedik, O Değer, H Mocan, E Erduran, C Karahan.   

Abstract

The purpose of this study is to evaluate the relationships between serum free fatty acids (FFA) and zinc, and attention deficit hyperactivity disorder (ADHD). Forty eight children with ADHD (33 boys, 15 girls) were included in the patient group and 45 healthy volunteer children (30 boys, 15 girls) constituted the control group. The mean serum FFA level in the patient group was 0.176 +/- 0.102 mEq/L and in control group, 0.562 +/- 0.225 mEq/L (p < .001). The mean serum zinc level of patient group was 60.6 +/- 9.9 micrograms/dl and that of the control group, 105.8 +/- 13.2 micrograms/dl (p < .001). A statistically significant correlation was found between zinc and FFA levels in the ADHD group. These findings indicate that zinc deficiency may play a role in aetiopathogenesis of ADHD. Although we observed decreased FFA levels in ADHD cases, it is necessary to determine whether this condition is a principal cause of ADHD or is secondary to zinc deficiency.

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Year:  1996        PMID: 8682903     DOI: 10.1111/j.1469-7610.1996.tb01395.x

Source DB:  PubMed          Journal:  J Child Psychol Psychiatry        ISSN: 0021-9630            Impact factor:   8.982


  16 in total

Review 1.  Long-chain polyunsaturated fatty acids in childhood developmental and psychiatric disorders.

Authors:  Alexandra J Richardson
Journal:  Lipids       Date:  2004-12       Impact factor: 1.880

Review 2.  The Role of Nutritional Supplements in the Treatment of ADHD: What the Evidence Says.

Authors:  Klaus W Lange; Joachim Hauser; Katharina M Lange; Ewelina Makulska-Gertruda; Yukiko Nakamura; Andreas Reissmann; Yuko Sakaue; Tomoyuki Takano; Yoshihiro Takeuchi
Journal:  Curr Psychiatry Rep       Date:  2017-02       Impact factor: 5.285

3.  Zinc for attention-deficit/hyperactivity disorder: placebo-controlled double-blind pilot trial alone and combined with amphetamine.

Authors:  L Eugene Arnold; Robert A Disilvestro; Dawn Bozzolo; Hernan Bozzolo; Lindsay Crowl; Soledad Fernandez; Yaser Ramadan; Susan Thompson; Xiaokui Mo; Mahmoud Abdel-Rasoul; Elizabeth Joseph
Journal:  J Child Adolesc Psychopharmacol       Date:  2011-02       Impact factor: 2.576

Review 4.  Role of zinc in maternal and child mental health.

Authors:  Ann M DiGirolamo; Manuel Ramirez-Zea
Journal:  Am J Clin Nutr       Date:  2009-01-28       Impact factor: 7.045

5.  Blood phospholipid fatty acid analysis of adults with and without attention deficit/hyperactivity disorder.

Authors:  Genevieve S Young; Nicole J Maharaj; Julie A Conquer
Journal:  Lipids       Date:  2004-02       Impact factor: 1.880

6.  Zinc status in attention-deficit/hyperactivity disorder: a systematic review and meta-analysis of observational studies.

Authors:  Seyed Mojtaba Ghoreishy; Sara Ebrahimi Mousavi; Farzaneh Asoudeh; Hamed Mohammadi
Journal:  Sci Rep       Date:  2021-07-16       Impact factor: 4.379

Review 7.  Nutritional supplements for the treatment of ADHD.

Authors:  Michael H Bloch; Jilian Mulqueen
Journal:  Child Adolesc Psychiatr Clin N Am       Date:  2014-08-12

8.  The role of vitamins and minerals in psychiatry.

Authors:  Stacey Cornish; Lewis Mehl-Madrona
Journal:  Integr Med Insights       Date:  2008-09-24

9.  Nutritional status of children with attention deficit hyperactivity disorder: a pilot study.

Authors:  Joy Y Kiddie; Margaret D Weiss; David D Kitts; Ryna Levy-Milne; Michael B Wasdell
Journal:  Int J Pediatr       Date:  2010-06-28

10.  Decreased Serum Cu/Zn SOD Associated with High Copper in Children with Attention Deficit Hyperactivity Disorder (ADHD).

Authors:  A J Russo
Journal:  J Cent Nerv Syst Dis       Date:  2010-05-04
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