Literature DB >> 8681298

Intraoperative radiotherapy for pancreatic carcinoma. Experimental and clinical studies.

T J Kinsella1, W F Sindelar.   

Abstract

Intraoperative radiotherapy (IORT) is an innovative treatment approach that has been tested in several Phase I-II studies and small Phase III trials in patients with resectable and unresectable pancreatic cancer. The technical approach and dose guidelines for adjacent normal tissues have been established in a series of experiments using a large animal (canine) model. This article reviews the experimental and clinical studies of IORT in cancer of the pancreas.

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Year:  1996        PMID： 8681298     DOI： 10.1002/(SICI)1097-0142(19960801)78:3<598::AID-CNCR40>3.0.CO;2-R

Source DB:  PubMed          Journal:  Cancer        ISSN： 0008-543X            Impact factor:   6.860


  9 in total

Review 1.  [Therapy of pancreatic adenocarcinoma].

Authors:  M Böhmig; B Wiedenmann; S Rosewicz
Journal:  Med Klin (Munich)       Date:  1999-11-15

2.  [3D-Ct-planned interstitial HDR brachytherapy + percutaneous irradiation and chemotherapy in inoperable pancreatic carcinoma. Methods and clinical outcome].

Authors:  L Pfreundner; K Baier; F Schwab; J Willner; K Bratengeier; M Flentje; H Feustel; K H Fuchs
Journal:  Strahlenther Onkol       Date:  1998-03       Impact factor: 3.621

3.  Neoadjuvant chemoradiation in patients with pancreatic adenocarcinoma.

Authors:  R Krempien; M W Muenter; W Harms; J Debus
Journal:  HPB (Oxford)       Date:  2006       Impact factor: 3.647

4.  Randomized phase II--study evaluating EGFR targeting therapy with cetuximab in combination with radiotherapy and chemotherapy for patients with locally advanced pancreatic cancer--PARC: study protocol [ISRCTN56652283].

Authors:  R Krempien; M W Muenter; P E Huber; S Nill; H Friess; C Timke; B Didinger; P Buechler; S Heeger; K K Herfarth; A Abdollahi; M W Buchler; J Debus
Journal:  BMC Cancer       Date:  2005-10-11       Impact factor: 4.430

5.  Commissioning, clinical implementation, and performance of the Mobetron 2000 for intraoperative radiation therapy.

Authors:  Landon S Wootton; Juergen Meyer; Edward Kim; Mark Phillips
Journal:  J Appl Clin Med Phys       Date:  2017-01       Impact factor: 2.102

6.  Intraoperative radiotherapy using a mobile electron LINAC: a retroperitoneal sarcoma case.

Authors:  A Sam Beddar; Sunil Krishnan
Journal:  J Appl Clin Med Phys       Date:  2005-08-12       Impact factor: 2.102

Review 7.  Intraoperative radiation therapy (IORT) in pancreatic cancer.

Authors:  Robert Krempien; Falk Roeder
Journal:  Radiat Oncol       Date:  2017-01-10       Impact factor: 3.481

8.  A phase II study of intraoperative radiotherapy using a low-energy x-ray source for resectable pancreatic cancer: a study protocol.

Authors:  Jun Won Kim; Yeona Cho; Hyung Sun Kim; Won Hoon Choi; Joon Seong Park; Ik Jae Lee
Journal:  BMC Surg       Date:  2019-03-07       Impact factor: 2.102

9.  Intraoperative radiation therapy induces immune response activity after pancreatic surgery.

Authors:  Yun Sun Lee; Hyung Sun Kim; Yeona Cho; Ik Jae Lee; Hyo Jung Kim; Da Eun Lee; Hyeon Woong Kang; Joon Seong Park
Journal:  BMC Cancer       Date:  2021-10-12       Impact factor: 4.430
  9 in total

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