Literature DB >> 8680870

Immunohistochemical detection of Bax and Bcl-2 proteins in gerbil hippocampus following transient forebrain ischemia.

A Hara1, T Iwai, M Niwa, T Uematsu, N Yoshimi, T Tanaka, H Mori.   

Abstract

Time-course expression of Bax and Bcl-2 proteins, identified as apoptosis-regulating molecules, was assessed in gerbil hippocampus following transient forebrain ischemia. Brain sections from animals sacrificed at 48, 72, 96 h and 7 days following 5 min ischemia were immunohistochemically evaluated using polyclonal antibodies specific for Bax and Bcl-2 proteins, respectively. The intensity of Bax expression in CA1 neurons increased with time and peaked at 72 h, and immediately disappeared at 96 h following 5 min ischemia. No expression of Bcl-2 in the CA1 neurons was recognized in all the time evaluated.

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Year:  1996        PMID： 8680870     DOI： 10.1016/0006-8993(95)01436-5

Source DB:  PubMed          Journal:  Brain Res        ISSN： 0006-8993            Impact factor:   3.252


  8 in total

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2.  Localization of Bax and Bcl-2 proteins, regulators of programmed cell death, in the human central nervous system.

Authors:  A Hara; Y Hirose; A Wang; N Yoshimi; T Tanaka; H Mori
Journal:  Virchows Arch       Date:  1996-11       Impact factor: 4.064

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4.  Choline availability modulates the expression of TGFbeta1 and cytoskeletal proteins in the hippocampus of developing rat brain.

Authors:  C D Albright; A Y Tsai; M H Mar; S H Zeisel
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5.  Radon inhalation protects against transient global cerebral ischemic injury in gerbils.

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Review 6.  Transcriptional regulation of the BCL-X gene by NF-kappaB is an element of hypoxic responses in the rat brain.

Authors:  J N Glasgow; J Qiu; D Rassin; M Grafe; T Wood; J R Perez-Pol
Journal:  Neurochem Res       Date:  2001-06       Impact factor: 3.996

7.  Transcriptome profiling of hippocampal CA1 after early-life seizure-induced preconditioning may elucidate new genetic therapies for epilepsy.

Authors:  L K Friedman; J Mancuso; A Patel; V Kudur; J R Leheste; S Iacobas; J Botta; D A Iacobas; D C Spray
Journal:  Eur J Neurosci       Date:  2013-04-04       Impact factor: 3.386

8.  Ginkgolide K protects SH‑SY5Y cells against oxygen‑glucose deprivation‑induced injury by inhibiting the p38 and JNK signaling pathways.

Authors:  Qiu Liu; Xueke Li; Liang Li; Zhiliang Xu; Jun Zhou; Wei Xiao
Journal:  Mol Med Rep       Date:  2018-07-23       Impact factor: 2.952
  8 in total

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