Literature DB >> 8679154

The rheological characteristics of nasal mucus in patients with rhinitis.

D Passàli1, L Bellussi, M Lauriello.   

Abstract

In this paper we have analyzed the physical properties of nasal mucus from 120 outpatients with rhinitis. We focused on the most relevant rheological features: viscosity, elasticity, adhesiveness, as well as ability to be spun ("spinability") or poured ("pourability"). A double-capillary type viscometer was used to measure viscosity and elasticity and the platinum ring method to measure adhesiveness. "Spinability" was measured with an automatic apparatus (Filancemetre Sefam) and "pourability" was determined by describing flow under gravity. Efficacy of nasal clearance was analyzed by measuring mucociliary transport time with an inert tracer using vegetal charcoal powder. Results showed that impaired nasal mucosal function in patients with rhinitis could be determined by studying rheological features in addition to measuring mucociliary activity. Information provided proved invaluable when considering possible treatment with agents affecting kinesis of nasal mucus.

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Year:  1995        PMID: 8679154     DOI: 10.1007/bf00178275

Source DB:  PubMed          Journal:  Eur Arch Otorhinolaryngol        ISSN: 0937-4477            Impact factor:   2.503


  8 in total

1.  Automatic device for measuring the 'spinability' of cervical mucus in woman.

Authors:  F C Chretien; B Ozenda; B Volochine
Journal:  Med Biol Eng Comput       Date:  1977-11       Impact factor: 2.602

Review 2.  Constituents of mucus and their separation.

Authors:  J M Creeth
Journal:  Br Med Bull       Date:  1978-01       Impact factor: 4.291

3.  Techniques for the measurement of the rheological properties of sputum.

Authors:  S S Davis
Journal:  Bull Physiopathol Respir (Nancy)       Date:  1973 Jan-Feb

4.  Field measurements of the "spinability" of bovine cervical mucus.

Authors:  J Burnett; F A Glover; G W Blair
Journal:  Biorheology       Date:  1967-01       Impact factor: 1.875

5.  A method for determining the viscoelastic properties of bioogical fluids.

Authors:  B Barnett; M J Dulfano; W Philippoff; C D Han
Journal:  Biorheology       Date:  1970-06       Impact factor: 1.875

6.  Experiences in the determination of nasal mucociliary transport time.

Authors:  D Passàli; L Bellussi; M Bianchini Ciampoli; E De Seta
Journal:  Acta Otolaryngol       Date:  1984 Mar-Apr       Impact factor: 1.494

7.  A micro double capillary method for rheologic measurements of lower airway secretions.

Authors:  C S Kim; B B Berkley; W M Abraham; A Wanner
Journal:  Bull Eur Physiopathol Respir       Date:  1982 Nov-Dec

8.  Normal values of mucociliary transport time in young subjects.

Authors:  D Passàli; M Bianchini Ciampoli
Journal:  Int J Pediatr Otorhinolaryngol       Date:  1985-07       Impact factor: 1.675

  8 in total
  2 in total

Review 1.  Micro- and macrorheology of mucus.

Authors:  Samuel K Lai; Ying-Ying Wang; Denis Wirtz; Justin Hanes
Journal:  Adv Drug Deliv Rev       Date:  2009-01-03       Impact factor: 15.470

2.  Development of a physiologically relevant dripping analytical method using simulated nasal mucus for nasal spray formulation analysis.

Authors:  Tina Masiuk; Parul Kadakia; Zhenyu Wang
Journal:  J Pharm Anal       Date:  2016-06-01
  2 in total

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