| Literature DB >> 8677746 |
O Rosnet1, H J Bühring, O deLapeyrière, N Beslu, C Lavagna, S Marchetto, I Rappold, H G Drexler, F Birg, R Rottapel, C Hannum, P Dubreuil, D Birnbaum.
Abstract
FLT3 is a receptor tyrosine kinase of 130-55 kDa expressed on normal bone marrow stem and early progenitor cells and on leukemic blasts from patients with acute leukemias. The FLT3 ligand, FL, is a new cytokine which acts on hematopoietic progenitors in synergy with other cytokines. FLT3 transduces FL-mediated signal through interaction with a number of cytoplasmic substrates.Entities:
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Year: 1996 PMID： 8677746 DOI： 10.1159/000203881
Source DB: PubMed Journal: Acta Haematol ISSN： 0001-5792 Impact factor: 2.195