Literature DB >> 8676317

Splenectomy in a general hospital.

J M Glass1, J M Gilbert.   

Abstract

Splenectomy is often performed in patients with malignant disease or trauma who are at a high risk of complications. In the long term, it increases the risk of infection by encapsulated bacteria. An audit was performed to determine the reasons for splenectomy in a district general hospital, to review the results and complications of surgery, and to see how often the patients were prescribed antibacterial prophylaxis. Twenty-eight patients underwent splenectomy in 3 years. The indication was haematological disease in 13 and trauma in four. In the remaining nine the spleen was removed either as part of a radical gastrectomy or during some other abdominal procedure. Six of the 28 patients had died, one within 30 days from disseminated intravascular coagulopathy following an emergency gastrectomy and splenectomy for haematemesis, two from progressive haematological malignant disease, two from non-haematological malignancy, and one from bronchopneumonia. Of the nine patients (32%) with complications, three required a further laparotomy. Most patients had been prescribed pneumococcal vaccine (85%) and prophylactic antibiotics (93%).

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Year:  1996        PMID: 8676317      PMCID: PMC1295735          DOI: 10.1177/014107689608900407

Source DB:  PubMed          Journal:  J R Soc Med        ISSN: 0141-0768            Impact factor:   18.000


  17 in total

Review 1.  Postsplenectomy sepsis.

Authors:  J H Shaw; C G Print
Journal:  Br J Surg       Date:  1989-10       Impact factor: 6.939

2.  Splenectomy in hematologic disorders. The ever-changing indications.

Authors:  M C Wilhelm; R E Jones; R McGehee; J S Mitchener; W R Sandusky; C E Hess
Journal:  Ann Surg       Date:  1988-05       Impact factor: 12.969

3.  Fatal post-splenectomy sepsis despite prophylaxis with penicillin and pneumococcal vaccine.

Authors:  D I Evans
Journal:  Lancet       Date:  1984-05-19       Impact factor: 79.321

4.  Impaired immune response of splenectomised patients to polyvalent pneumococcal vaccine.

Authors:  S W Hosea; C G Burch; E J Brown; R A Berg; M M Frank
Journal:  Lancet       Date:  1981-04-11       Impact factor: 79.321

5.  Pneumococcal vaccination after splenectomy: survey of hospital and primary care records.

Authors:  P Kinnersley; C E Wilkinson; J Srinivasan
Journal:  BMJ       Date:  1993-11-27

6.  Long term management of patients after splenectomy.

Authors:  M McMullin; G Johnston
Journal:  BMJ       Date:  1993-11-27

Review 7.  Long-term complications of laparotomy in Hodgkin's disease.

Authors:  M Jockovich; N P Mendenhall; M D Sombeck; J L Talbert; E M Copeland; K I Bland
Journal:  Ann Surg       Date:  1994-06       Impact factor: 12.969

Review 8.  Postsplenectomy sepsis and its mortality rate: actual versus perceived risks.

Authors:  R J Holdsworth; A D Irving; A Cuschieri
Journal:  Br J Surg       Date:  1991-09       Impact factor: 6.939

9.  Changing role of splenectomy for hematologic disease.

Authors:  K R Marble; P J Deckers; K A Kern
Journal:  J Surg Oncol       Date:  1993-03       Impact factor: 3.454

10.  Complications related to 234 staging laparotomies performed in the Intergroup Hodgkin's Disease in Childhood study.

Authors:  D M Hays; J L Ternberg; T T Chen; M P Sullivan; L M Fuller; M Tefft; F Kung; G Gilchrist; C Fryer; R N Heller
Journal:  Surgery       Date:  1984-09       Impact factor: 3.982

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  2 in total

1.  An audit of splenectomies in a teaching hospital in North India. Are postsplenectomy guidelines being complied with?

Authors:  M Deodhar; N Kakkar
Journal:  J Clin Pathol       Date:  2004-04       Impact factor: 3.411

2.  Splenectomy for hematological disorders in Iranian pediatric patients: a single center study.

Authors:  Bibi Shahin Shamsian; Mohammad Thaghi Arzanian; Raheleh Kaviani; Samin Alavi; Mona Hedayat; Nima Rezaei
Journal:  Iran J Pediatr       Date:  2012-06       Impact factor: 0.364

  2 in total

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