| Literature DB >> 8676132 |
F Fullas1, D M Brown, M C Wani, M E Wall, T E Chagwedera, N R Farnsworth, J M Pezzuto, A D Kinghorn.
Abstract
A new polyacetylenic diepoxide compound, gummiferol [1] was isolated from the leaves of Adenia gummifera by KB cytotoxicity-guided fractionation. Compound 1 exhibited significant activity against the KB human cell line and a broad cytotoxic spectrum against other human cancer cell lines. The structure of 1 was established primarily on the basis of its spectral data.Entities:
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Year: 1995 PMID： 8676132 DOI： 10.1021/np50124a027
Source DB: PubMed Journal: J Nat Prod ISSN： 0163-3864 Impact factor: 4.050