Literature DB >> 8674540

Selective control of cytosolic glutathione peroxidase and phospholipid hydroperoxide glutathione peroxidase mRNA stability by selenium supply.

G Bermano1, J R Arthur, J E Hesketh.   

Abstract

Selenium depletion of H4 hepatoma cells reduced cytosolic glutathione peroxidase (cGSH-Px) mRNA abundance but had no effect on phospholipid hydroperoxide glutathione peroxidase (PHGSH-Px) mRNA abundance. Actinomycin D chase experiments showed that selenium depletion had no effect on the stability of PHGSH-Px mRNA but decreased the stability of cGSH-Px mRNA. In Se-replete cells puromycin decreased the stability of both cGSH-Px and PHGSH-Px mRNAs. The results suggest that when selenium supply is limiting PHGSH-Px mRNA translation is maintained more than that of cGSH-Px mRNA, and thus more cGSH-Px mRNA is released from polysomes and degraded.

Entities:  

Mesh：

Substances：

Year:  1996        PMID： 8674540     DOI： 10.1016/0014-5793(96)00493-0

Source DB:  PubMed          Journal:  FEBS Lett        ISSN： 0014-5793            Impact factor:   4.124


  18 in total

1.  Regulation of calpain and calpastatin in differentiating myoblasts: mRNA levels, protein synthesis and stability.

Authors:  S Barnoy; L Supino-Rosin; N S Kosower
Journal:  Biochem J       Date:  2000-10-15       Impact factor: 3.857

2.  Selenium deficiency reduces the abundance of mRNA for Se-dependent glutathione peroxidase 1 by a UGA-dependent mechanism likely to be nonsense codon-mediated decay of cytoplasmic mRNA.

Authors:  P M Moriarty; C C Reddy; L E Maquat
Journal:  Mol Cell Biol       Date:  1998-05       Impact factor: 4.272

3.  Selective up-regulation of human selenoproteins in response to oxidative stress.

Authors:  Zahia Touat-Hamici; Yona Legrain; Anne-Laure Bulteau; Laurent Chavatte
Journal:  J Biol Chem       Date:  2014-04-04       Impact factor: 5.157

4.  T-cell Expression of IL10 Is Essential for Tumor Immune Surveillance in the Small Intestine.

Authors:  Kristen L Dennis; Abdulrahman Saadalla; Nichole R Blatner; Shuya Wang; Vysak Venkateswaran; Fotini Gounari; Hilde Cheroutre; Casey T Weaver; Axel Roers; Nejat K Egilmez; Khashayarsha Khazaie
Journal:  Cancer Immunol Res       Date:  2015-04-08       Impact factor: 11.151

5.  Effects of dietary selenium on post-ischemic expression of antioxidant mRNA.

Authors:  Kylie Venardos; Kevin Ashton; John Headrick; Anthony Perkins
Journal:  Mol Cell Biochem       Date:  2005-02       Impact factor: 3.396

6.  Dietary selenium as a modulator of PCB 126-induced hepatotoxicity in male Sprague-Dawley rats.

Authors:  Ian K Lai; Yingtao Chai; Donald Simmons; Walter H Watson; Rommel Tan; Wanda M Haschek; Kai Wang; Bingxuan Wang; Gabriele Ludewig; Larry W Robertson
Journal:  Toxicol Sci       Date:  2011-08-24       Impact factor: 4.849

7.  Nonsense-mediated decay of mRNA for the selenoprotein phospholipid hydroperoxide glutathione peroxidase is detectable in cultured cells but masked or inhibited in rat tissues.

Authors:  X Sun; X Li; P M Moriarty; T Henics; J P LaDuca; L E Maquat
Journal:  Mol Biol Cell       Date:  2001-04       Impact factor: 4.138

Review 8.  Chemopreventive mechanisms of selenium.

Authors:  G F Combs
Journal:  Med Klin (Munich)       Date:  1999-10-15

9.  Nonsense-mediated decay of glutathione peroxidase 1 mRNA in the cytoplasm depends on intron position.

Authors:  X Sun; P M Moriarty; L E Maquat
Journal:  EMBO J       Date:  2000-09-01       Impact factor: 11.598

Review 10.  Glutathione peroxidase-1 in health and disease: from molecular mechanisms to therapeutic opportunities.

Authors:  Edith Lubos; Joseph Loscalzo; Diane E Handy
Journal:  Antioxid Redox Signal       Date:  2011-04-10       Impact factor: 8.401
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.