Literature DB >> 867449

Formation of a steroidal allyl alcohol in the mammary glands of mice.

M Mori, B Tamaoki.   

Abstract

After incubation of [4-14C]progesterone with cell-free homogenates of mouse mammary gland in the presence of NADPH, [14C]-labeled 4-pregnene-3alpha, 20alpha-diol was identified as a metabolite, besides 20alpha-hydroxy-4-pregnene-3-one which was the major metabolite.

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Year:  1977        PMID: 867449     DOI: 10.1016/0039-128x(77)90071-x

Source DB:  PubMed          Journal:  Steroids        ISSN: 0039-128X            Impact factor:   2.668


  1 in total

1.  Expression of progesterone metabolizing enzyme genes (AKR1C1, AKR1C2, AKR1C3, SRD5A1, SRD5A2) is altered in human breast carcinoma.

Authors:  Michael J Lewis; John P Wiebe; J Godfrey Heathcote
Journal:  BMC Cancer       Date:  2004-06-22       Impact factor: 4.430

  1 in total

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