Literature DB >> 8673601

Structural basis for specificity of Grb2-SH2 revealed by a novel ligand binding mode.

J Rahuel, B Gay, D Erdmann, A Strauss, C Garcia-Echeverría, P Furet, G Caravatti, H Fretz, J Schoepfer, M G Grütter.   

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Year:  1996        PMID: 8673601     DOI: 10.1038/nsb0796-586

Source DB:  PubMed          Journal:  Nat Struct Biol        ISSN: 1072-8368


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2.  Two mechanisms activate PTPalpha during mitosis.

Authors:  X M Zheng; D Shalloway
Journal:  EMBO J       Date:  2001-11-01       Impact factor: 11.598

3.  Specificity and affinity motifs for Grb2 SH2-ligand interactions.

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Journal:  Proc Natl Acad Sci U S A       Date:  2002-06-25       Impact factor: 11.205

4.  Peptide bicycles that inhibit the Grb2 SH2 domain.

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5.  Loops govern SH2 domain specificity by controlling access to binding pockets.

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7.  Defining SH2 domain and PTP specificity by screening combinatorial peptide libraries.

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Journal:  Methods       Date:  2007-07       Impact factor: 3.608

8.  Conformationally constrained peptidomimetic inhibitors of signal transducer and activator of transcription. 3: Evaluation and molecular modeling.

Authors:  Pijus K Mandal; Donald Limbrick; David R Coleman; Garrett A Dyer; Zhiyong Ren; J Sanderson Birtwistle; Chiyi Xiong; Xiaomin Chen; James M Briggs; John S McMurray
Journal:  J Med Chem       Date:  2009-04-23       Impact factor: 7.446

9.  Structural examination of ring-closing metathesis-derived 15-member macrocycles as Grb2 SH2 domain-binding tetrapeptide mimetics.

Authors:  Fa Liu; Karen M Worthy; Lakshman K Bindu; Robert J Fisher; Terrence R Burke
Journal:  J Org Chem       Date:  2007-11-09       Impact factor: 4.354

10.  Crystal structure of the tyrosine kinase domain of the hepatocyte growth factor receptor c-Met and its complex with the microbial alkaloid K-252a.

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