Literature DB >> 8667290

Patch-clamp study on membrane properties and transmitter activated currents of rabbit area postrema neurons.

K Jahn1, J Bufler, A Weindl, T Arzberger, H Hatt.   

Abstract

Using the patch-clamp technique in combination wit sliced tissue preparation the membrane properties of newborn rabbit area postrema neurons were investigated. The neurons responded upon depolarization with a fast Na+-current followed by an inactivating and non-inactivating K+-current. GABA-activated currents were investigated resulting in a large C1-(-)conductance, indicating the expression of GABAA-receptors. The expression of glutamate receptor mRNA was studied by in situ hybridization and electrophysiological measurements of these receptors by means of the patch-clamp technique. As a main result it was found that ionotropic glutamate receptors in the area postrema are composed of "flop" variants of the GluA-, GluB- and GluC-subunits.

Entities:  

Mesh：

Substances：

Year:  1996        PMID： 8667290     DOI： 10.1007/bf00225825

Source DB:  PubMed          Journal:  J Comp Physiol A            Impact factor:   1.836


  28 in total

1.  GABA-mediated inhibition of medullary vasomotor neurones by area postrema stimulation in rats.

Authors:  M K Sun; K M Spyer
Journal:  J Physiol       Date:  1991-05       Impact factor: 5.182

2.  A thin slice preparation for patch clamp recordings from neurones of the mammalian central nervous system.

Authors:  F A Edwards; A Konnerth; B Sakmann; T Takahashi
Journal:  Pflugers Arch       Date:  1989-09       Impact factor: 3.657

3.  Patch-clamp study of ion channels activated by GABA and glycine in cultured cerebellar neurons of the mouse.

Authors:  S Huck; H D Lux
Journal:  Neurosci Lett       Date:  1987-08-18       Impact factor: 3.046

Review 4.  Mechanism of anion permeation through channels gated by glycine and gamma-aminobutyric acid in mouse cultured spinal neurones.

Authors:  J Bormann; O P Hamill; B Sakmann
Journal:  J Physiol       Date:  1987-04       Impact factor: 5.182

5.  Prediction of repetitive firing behaviour from voltage clamp data on an isolated neurone soma.

Authors:  J A Connor; C F Stevens
Journal:  J Physiol       Date:  1971-02       Impact factor: 5.182

6.  Patch-clamp study of membrane properties and GABA-activated currents of rat magnocellular supraoptic neurons in thin slice preparation.

Authors:  J Bufler; K Jahn; A Weindl; T Arzberger; H Hatt
Journal:  Neurobiology (Bp)       Date:  1994

7.  Immunocytochemical localization of glutamic acid decarboxylase (GAD) and glutamine synthetase (GS) in the area postrema of the cat. Light and electron microscopy.

Authors:  F E D'Amelio; W R Mehler; M A Gibbs; L F Eng; J Y Wu
Journal:  Brain Res       Date:  1987-05-05       Impact factor: 3.252

8.  Gated currents generate single spike activity in amacrine cells of the tiger salamander retina.

Authors:  S Barnes; F Werblin
Journal:  Proc Natl Acad Sci U S A       Date:  1986-03       Impact factor: 11.205

9.  Electrophysiological and morphological properties of granule cells: patch-clamp recordings of newborn rabbit olfactory bulb slices.

Authors:  J Bufler; T Opitz; H Hatt
Journal:  Neurosci Lett       Date:  1993-10-29       Impact factor: 3.046

10.  Two fast transient current components during voltage clamp on snail neurons.

Authors:  E Neher
Journal:  J Gen Physiol       Date:  1971-07       Impact factor: 4.086
View more
  2 in total

1.  Role of the hyperpolarization-activated cation current (Ih) in pacemaker activity in area postrema neurons of rat brain slices.

Authors:  Makoto Funahashi; Yoshihiro Mitoh; Atsushi Kohjitani; Ryuji Matsuo
Journal:  J Physiol       Date:  2003-08-01       Impact factor: 5.182

2.  Excitatory effect of ATP on rat area postrema neurons.

Authors:  Masaru Sorimachia; Minoru Wakamoria; Norio Akaikeb
Journal:  Purinergic Signal       Date:  2006-05-30       Impact factor: 3.765
  2 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.