Literature DB >> 866648

Radiosensitization of normal tissue by chloroquine.

J F Utley, C R Sachatello, Y Maruyama, J Avila, R King.   

Abstract

Severe radiation reaction with chest wall necrosis occurred following 5,000 rads of 60Co irradiation. The patient was arthritic and on chloroquine therapy. This delayed reaction was due to chloroquine radiosensitization. Rats treated with combined chloroquine and chest wall irradiation were compared to rats receiving irradiation alone. The acute radiation reaction was greater in the drug treated animals.

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Year:  1977        PMID: 866648     DOI: 10.1148/124.1.255

Source DB:  PubMed          Journal:  Radiology        ISSN: 0033-8419            Impact factor:   11.105


  1 in total

1.  FET-PET-based reirradiation and chloroquine in patients with recurrent glioblastoma: first tolerability and feasibility results.

Authors:  Angelika Bilger; Martin-Immanuel Bittner; Anca-L Grosu; Nicole Wiedenmann; Philipp T Meyer; Elke Firat; Gabriele Niedermann; Wolfgang A Weber; Dušan Milanović
Journal:  Strahlenther Onkol       Date:  2014-06-14       Impact factor: 3.621

  1 in total

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