Literature DB >> 8666289

Cloning and chromosomal localization of a novel gene-encoding a human beta 2-integrin alpha subunit.

D A Wong1, E M Davis, M LeBeau, T A Springer.   

Abstract

We isolated a partial genomic clone encoding ITGAD, a novel beta 2-integrin alpha subunit. The ITGAD gene is highly homologous to the three previously known alpha subunit-encoding genes, that compose the beta 2 integrin family, in deduced amino acid sequence, intron/exon structure and mapping location (chromosome 16p11).

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Year:  1996        PMID： 8666289     DOI： 10.1016/0378-1119(95)00869-1

Source DB:  PubMed          Journal:  Gene        ISSN： 0378-1119            Impact factor:   3.688


  6 in total

1.  Expression Profile of the Integrin Receptor Subunits in the Guinea Pig Sclera.

Authors:  Kevin K Wang; Ravikanth Metlapally; Christine F Wildsoet
Journal:  Curr Eye Res       Date:  2017-01-17       Impact factor: 2.424

Review 2.  beta2-integrins in demyelinating disease: not adhering to the paradigm.

Authors:  Xianzhen Hu; Jillian E Wohler; Kari J Dugger; Scott R Barnum
Journal:  J Leukoc Biol       Date:  2009-12-09       Impact factor: 4.962

3.  Two Novel Frame Shift, Recurrent and De Novo Mutations in the ITGB2 (CD18) Gene Causing Leukocyte Adhesion Deficiency in a Highly Inbred North African Population.

Authors:  D. M. Fathallah; T. Jamal; M. R. Barbouche; M. Bejaoui; M. Ben Hariz; K. Dellagi
Journal:  J Biomed Biotechnol       Date:  2001

4.  Integrin αDβ2 (CD11d/CD18) is expressed by human circulating and tissue myeloid leukocytes and mediates inflammatory signaling.

Authors:  Yasunari Miyazaki; Adriana Vieira-de-Abreu; Estelle S Harris; Amrapali M Shah; Andrew S Weyrich; Hugo C Castro-Faria-Neto; Guy A Zimmerman
Journal:  PLoS One       Date:  2014-11-21       Impact factor: 3.240

5.  Novel ITGB2 Mutation Is Responsible for a Severe Form of Leucocyte Adhesion Deficiency Type 1.

Authors:  Ahmed Bouhouche; Yasmin Tabache; Omar Askander; Hicham Charoute; Nada Mesnaoui; Lamiae Belayachi; Naima El Hafidi; Houyam Hardizi; Elmostafa El Fahime; Naima Erreimi; Abdelhamid Barakat; Mohammed Khattab; Fouad Seghrouchni; Amine El Hassani
Journal:  Biomed Res Int       Date:  2022-03-03       Impact factor: 3.411

Review 6.  β2 Integrin CD11d/CD18: From Expression to an Emerging Role in Staged Leukocyte Migration.

Authors:  Eoin N Blythe; Lynne C Weaver; Arthur Brown; Gregory A Dekaban
Journal:  Front Immunol       Date:  2021-11-08       Impact factor: 7.561
  6 in total

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