Literature DB >> 8664544

Regulation of adipocyte gene expression and differentiation by peroxisome proliferator activated receptor gamma.

P Tontonoz1, E Hu, B M Spiegelman.   

Abstract

Peroxisome proliferator activated receptor (PPAR)gamma is an orphan member of the nuclear hormone receptor superfamily and is expressed at high levels specifically in adipose tissue. Recent data suggest that this factor is a central regulator of adipocyte gene expression and differentiation. Fibroblastic cell lines that express PPARgamma ectopically can be induced to differentiate into fat cells by a variety of lipids and lipid-like activators of PPARs, suggesting that this protein may function to link adipogenesis with systemic lipid metabolism.

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Year:  1995        PMID： 8664544     DOI： 10.1016/0959-437x(95)80025-5

Source DB:  PubMed          Journal:  Curr Opin Genet Dev        ISSN： 0959-437X            Impact factor:   5.578


  104 in total

1.  Opposing roles of pRB and p107 in adipocyte differentiation.

Authors:  M Classon; B K Kennedy; R Mulloy; E Harlow
Journal:  Proc Natl Acad Sci U S A       Date:  2000-09-26       Impact factor: 11.205

2.  oxHDL decreases the expression of CD36 on human macrophages through PPARgamma and p38 MAP kinase dependent mechanisms.

Authors:  Jingyi Ren; Wenying Jin; Hong Chen
Journal:  Mol Cell Biochem       Date:  2010-05-11       Impact factor: 3.396

3.  Postnatal rosiglitazone administration to neonatal rat pups does not alter the young adult metabolic phenotype.

Authors:  Nghia C Truong; Afshan Abbasi; Reiko Sakurai; W N Paul Lee; John S Torday; Virender K Rehan
Journal:  Neonatology       Date:  2011-11-10       Impact factor: 4.035

Review 4.  Adipose tissue and inflammatory bowel disease pathogenesis.

Authors:  Christopher Fink; Iordanes Karagiannides; Kyriaki Bakirtzi; Charalabos Pothoulakis
Journal:  Inflamm Bowel Dis       Date:  2012-03-08       Impact factor: 5.325

Review 5.  Submaximal PPARγ activation and endothelial dysfunction: new perspectives for the management of cardiovascular disorders.

Authors:  Pitchai Balakumar; Sonam Kathuria
Journal:  Br J Pharmacol       Date:  2012-08       Impact factor: 8.739

Review 6.  The EBF/Olf/Collier family of transcription factors: regulators of differentiation in cells originating from all three embryonal germ layers.

Authors:  David Liberg; Mikael Sigvardsson; Peter Akerblad
Journal:  Mol Cell Biol       Date:  2002-12       Impact factor: 4.272

7.  Rosiglitazone modifies the adipogenic potential of human muscle satellite cells.

Authors:  P De Coppi; G Milan; A Scarda; L Boldrin; C Centobene; M Piccoli; M Pozzobon; C Pilon; C Pagano; P Gamba; R Vettor
Journal:  Diabetologia       Date:  2006-06-24       Impact factor: 10.122

8.  Antidiabetic thiazolidinediones induce ductal differentiation but not apoptosis in pancreatic cancer cells.

Authors:  Elisabetta Ceni; Tommaso Mello; Mirko Tarocchi; David-W Crabb; Anna Caldini; Pietro Invernizzi; Calogero Surrenti; Stefano Milani; Andrea Galli
Journal:  World J Gastroenterol       Date:  2005-02-28       Impact factor: 5.742

9.  Nuclear receptor profile in calvarial bone cells undergoing osteogenic versus adipogenic differentiation.

Authors:  Flavia Q Pirih; Rosette Abayahoudian; David Elashoff; Farhad Parhami; Jeanne M Nervina; Sotirios Tetradis
Journal:  J Cell Biochem       Date:  2008-12-01       Impact factor: 4.429

10.  Peripheral blood mononuclear cells: a potential source of homeostatic imbalance markers associated with obesity development.

Authors:  Paula Oliver; Bàrbara Reynés; Antoni Caimari; Andreu Palou
Journal:  Pflugers Arch       Date:  2013-02-20       Impact factor: 3.657
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