Literature DB >> 8664040

The importance of a multidisciplinary group in the treatment of soft tissue sarcomas.

T Wiklund1, R Huuhtanen, C Blomqvist, E Tukiainen, M Virolainen, P Virkkunen, S Asko-Seljavaara, J M Björkenheim, I Elomaa.   

Abstract

In 1987, a multidisciplinary soft tissue sarcoma (STS) group was established and a treatment protocol was set up. By 1993, there were 193 patients with a diagnosis of STS of the superficial trunk or extremities. 134 patients were referred with primary (stage M0) tumours and treated with curative or palliative intention. Nine amputations were performed. 94 (70%) patients were treated with wide or compartment surgery (n = 62) or marginal surgery combined with postoperative radiotherapy (n = 32). According to the protocol, these patients had received adequate treatment. 18 patients have recurred locally (13%) (median follow-up: 36 months). 12 were salvaged. 33 had metastases. The estimated 3-year survival, local control and disease-free survival rates are 79, 87 and 69%, respectively. These results compare favourably with previously published results from this hospital and from a nationwide study. The improved results emphasise the importance of a multidisciplinary STS group.

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Year:  1996        PMID: 8664040     DOI: 10.1016/0959-8049(95)00520-x

Source DB:  PubMed          Journal:  Eur J Cancer        ISSN: 0959-8049            Impact factor:   9.162


  13 in total

1.  Comparative genomic hybridization of malignant fibrous histiocytoma reveals a novel prognostic marker.

Authors:  M L Larramendy; M Tarkkanen; C Blomqvist; M Virolainen; T Wiklund; S Asko-Seljavaara; I Elomaa; S Knuutila
Journal:  Am J Pathol       Date:  1997-10       Impact factor: 4.307

2.  Relevance of Reference Centers in Sarcoma Care and Quality Item Evaluation: Results from the Prospective Registry of the Spanish Group for Research in Sarcoma (GEIS).

Authors:  Javier Martin-Broto; Nadia Hindi; Josefina Cruz; Javier Martinez-Trufero; Claudia Valverde; Luis M De Sande; Angeles Sala; Lorena Bellido; Ana De Juan; Jordi Rubió-Casadevall; Roberto Diaz-Beveridge; Ricardo Cubedo; Oscar Tendero; Diego Salinas; Isidro Gracia; Rafael Ramos; Silvia Baguè; Antonio Gutierrez; José Duran-Moreno; Antonio Lopez-Pousa
Journal:  Oncologist       Date:  2018-11-08

Review 3.  Recent advances: oncology.

Authors:  M H Tattersall; H Thomas
Journal:  BMJ       Date:  1999-02-13

Review 4.  Centralised treatment of soft tissue sarcomas in adults.

Authors:  Luis A Pérez Romasanta; Angel Montero Luis; Ramona Verges Capdevila; Alfonso Mariño Cotelo; José M Rico Pérez
Journal:  Clin Transl Oncol       Date:  2008-02       Impact factor: 3.405

5.  Comparison of the Ki-67 score and S-phase fraction as prognostic variables in soft-tissue sarcoma.

Authors:  R L Huuhtanen; C P Blomqvist; T A Wiklund; T O Böhling; M J Virolainen; E J Tukiainen; B Tribukait; L C Andersson
Journal:  Br J Cancer       Date:  1999-02       Impact factor: 7.640

6.  The adhesion molecule CD44v6 is associated with a high risk for local recurrence in adult soft tissue sarcomas.

Authors:  S Maula; R L Huuhtanen; C P Blomqvist; T A Wiklund; P Laurila; R Ristamäki
Journal:  Br J Cancer       Date:  2001-01       Impact factor: 7.640

7.  Improved prognosis in soft-tissue sarcoma of extremity and trunk wall.

Authors:  Mika M Sampo; Katariina Klintrup; Erkki J Tukiainen; Tom O Böhling; Carl P Blomqvist
Journal:  Acta Orthop       Date:  2016-06-20       Impact factor: 3.717

8.  Processes and outcomes of care for soft tissue sarcoma of the extremities.

Authors:  Lawrence Paszat; Brian O'Sullivan; Robert Bell; Vivien Bramwell; Patti Groome; William Mackillop; Emma Bartfay; Eric Holowaty
Journal:  Sarcoma       Date:  2002

9.  Disease incidence and results of extremity lesion treatment: mersey region soft tissue sarcomas (1975-1985).

Authors:  M J Jane; P J Hughes
Journal:  Sarcoma       Date:  1998

Review 10.  Soft Tissue Coverage of the Lower Limb following Oncological Surgery.

Authors:  Christine Radtke; Martin Panzica; Khaled Dastagir; Christian Krettek; Peter M Vogt
Journal:  Front Oncol       Date:  2016-01-13       Impact factor: 6.244

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