Literature DB >> 8662541

The POU factor Oct-6 and Schwann cell differentiation.

M Jaegle1, W Mandemakers, L Broos, R Zwart, A Karis, P Visser, F Grosveld, D Meijer.   

Abstract

The POU transcription factor Oct-6, also known as SCIP or Tst-1, has been implicated as a major transcriptional regulator in Schwann cell differentiation. Microscopic and immunochemical analysis of sciatic nerves of Oct-6(-/-) mice at different stages of postnatal development reveals a delay in Schwann cell differentiation, with a transient arrest at the promyelination stage. Thus, Oct-6 appears to be required for the transition of promyelin cells to myelinating cells. Once these cells progress past this point, Oct-6 is no longer required, and myelination occurs normally.

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Year:  1996        PMID： 8662541     DOI： 10.1126/science.273.5274.507

Source DB:  PubMed          Journal:  Science        ISSN： 0036-8075            Impact factor:   47.728


  94 in total

1.  The transcription factor Sox10 is a key regulator of peripheral glial development.

Authors:  S Britsch; D E Goerich; D Riethmacher; R I Peirano; M Rossner; K A Nave; C Birchmeier; M Wegner
Journal:  Genes Dev       Date:  2001-01-01       Impact factor: 11.361

2.  A distal Schwann cell-specific enhancer mediates axonal regulation of the Oct-6 transcription factor during peripheral nerve development and regeneration.

Authors:  W Mandemakers; R Zwart; M Jaegle; E Walbeehm; P Visser; F Grosveld; D Meijer
Journal:  EMBO J       Date:  2000-06-15       Impact factor: 11.598

3.  Repression of Ets-2-induced transactivation of the tau interferon promoter by Oct-4.

Authors:  T Ezashi; D Ghosh; R M Roberts
Journal:  Mol Cell Biol       Date:  2001-12       Impact factor: 4.272

4.  A distal upstream enhancer from the myelin basic protein gene regulates expression in myelin-forming schwann cells.

Authors:  R Forghani; L Garofalo; D R Foran; H F Farhadi; P Lepage; T J Hudson; I Tretjakoff; P Valera; A Peterson
Journal:  J Neurosci       Date:  2001-06-01       Impact factor: 6.167

Review 5.  Signals that determine Schwann cell identity.

Authors:  K R Jessen; R Mirsky
Journal:  J Anat       Date:  2002-04       Impact factor: 2.610

6.  A cell type-specific allele of the POU gene Oct-6 reveals Schwann cell autonomous function in nerve development and regeneration.

Authors:  Merhnaz Ghazvini; Wim Mandemakers; Martine Jaegle; Marko Piirsoo; Siska Driegen; Manousos Koutsourakis; Xsander Smit; Frank Grosveld; Dies Meijer
Journal:  EMBO J       Date:  2002-09-02       Impact factor: 11.598

7.  The Sox-2 regulatory regions display their activities in two distinct types of multipotent stem cells.

Authors:  Satoru Miyagi; Tetsuichiro Saito; Ken-ichi Mizutani; Norihisa Masuyama; Yukiko Gotoh; Atsushi Iwama; Hiromitsu Nakauchi; Shinji Masui; Hitoshi Niwa; Masazumi Nishimoto; Masami Muramatsu; Akihiko Okuda
Journal:  Mol Cell Biol       Date:  2004-05       Impact factor: 4.272

8.  The nucleosome remodeling and deacetylase chromatin remodeling (NuRD) complex is required for peripheral nerve myelination.

Authors:  Holly Hung; Rebecca Kohnken; John Svaren
Journal:  J Neurosci       Date:  2012-02-01       Impact factor: 6.167

9.  Essential role of POU-domain factor Brn-3c in auditory and vestibular hair cell development.

Authors:  M Xiang; L Gan; D Li; Z Y Chen; L Zhou; B W O'Malley; W Klein; J Nathans
Journal:  Proc Natl Acad Sci U S A       Date:  1997-08-19       Impact factor: 11.205

10.  Calcineurin/NFAT signaling is required for neuregulin-regulated Schwann cell differentiation.

Authors:  Shih-Chu Kao; Hai Wu; Jianming Xie; Ching-Pin Chang; Jeffrey A Ranish; Isabella A Graef; Gerald R Crabtree
Journal:  Science       Date:  2009-01-30       Impact factor: 47.728
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