Literature DB >> 8662537

Multicolor spectral karyotyping of human chromosomes.

E Schröck1, S du Manoir, T Veldman, B Schoell, J Wienberg, M A Ferguson-Smith, Y Ning, D H Ledbetter, I Bar-Am, D Soenksen, Y Garini, T Ried.   

Abstract

The simultaneous and unequivocal discernment of all human chromosomes in different colors would be of significant clinical and biologic importance. Whole-genome scanning by spectral karyotyping allowed instantaneous visualization of defined emission spectra for each human chromosome after fluorescence in situ hybridization. By means of computer separation (classification) of spectra, spectrally overlapping chromosome-specific DNA probes could be resolved, and all human chromosomes were simultaneously identified.

Entities:  

Mesh：

Substances：

Year:  1996        PMID： 8662537     DOI： 10.1126/science.273.5274.494

Source DB:  PubMed          Journal:  Science        ISSN： 0036-8075            Impact factor:   47.728


  276 in total

Review 1.  Imaging of single DNA molecule: applications to high-resolution genomic studies.

Authors:  J Herrick; A Bensimon
Journal:  Chromosome Res       Date:  1999       Impact factor: 5.239

2.  Gone FISHin' for genes.

Authors:  D J Demetrick
Journal:  CMAJ       Date:  1999-11-02       Impact factor: 8.262

3.  Multilocus genetic analysis of single interphase cells by spectral imaging.

Authors:  J Fung; H U Weier; J D Goldberg; R A Pedersen
Journal:  Hum Genet       Date:  2000-12       Impact factor: 4.132

4.  Computed tomography-based spectral imaging for fluorescence microscopy.

Authors:  B K Ford; C E Volin; S M Murphy; R M Lynch; M R Descour
Journal:  Biophys J       Date:  2001-02       Impact factor: 4.033

5.  Evidence of chromosomal instability in prostate cancer determined by spectral karyotyping (SKY) and interphase fish analysis.

Authors:  B Beheshti; P C Park; J M Sweet; J Trachtenberg; M A Jewett; J A Squire
Journal:  Neoplasia       Date:  2001 Jan-Feb       Impact factor: 5.715

6.  An optimized probe set for the detection of small interchromosomal aberrations by use of 24-color FISH.

Authors:  J Azofeifa; C Fauth; J Kraus; C Maierhofer; S Langer; A Bolzer; J Reichman; S Schuffenhauer; M R Speicher
Journal:  Am J Hum Genet       Date:  2000-04-04       Impact factor: 11.025

7.  Differentially painting human chromosome arms with combined binary ratio-labeling fluorescence in situ hybridization.

Authors:  J Wiegant; V Bezrookove; C Rosenberg; H J Tanke; A K Raap; H Zhang; M Bittner; J M Trent; P Meltzer
Journal:  Genome Res       Date:  2000-06       Impact factor: 9.043

8.  Identification of a high frequency of chromosomal rearrangements in the centromeric regions of prostate cancer cell lines by sequential giemsa banding and spectral karyotyping.

Authors:  B Beheshti; J Karaskova; P C Park; J A Squire; B G Beatty
Journal:  Mol Diagn       Date:  2000-03

9.  Quantifying single gene copy number by measuring fluorescent probe lengths on combed genomic DNA.

Authors:  J Herrick; X Michalet; C Conti; C Schurra; A Bensimon
Journal:  Proc Natl Acad Sci U S A       Date:  2000-01-04       Impact factor: 11.205

Review 10.  The role of fluorescence in situ hybridization technologies in molecular diagnostics and disease management.

Authors:  W King; J Proffitt; L Morrison; J Piper; D Lane; S Seelig
Journal:  Mol Diagn       Date:  2000-12
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.