Literature DB >> 8660968

A human gene (DDX10) encoding a putative DEAD-box RNA helicase at 11q22-q23.

K Savitsky1, Y Ziv, A Bar-Shira, S Gilad, D A Tagle, S Smith, T Uziel, S Sfez, J Nahmias, A Sartiel, R L Eddy, T B Shows, F S Collins, Y Shiloh, G Rotman.   

Abstract

A human gene encoding a putative RNA helicase, designated DDX10, was identified 400 kb telomeric to the ataxia-telangiectasia gene at chromosome 11q22-q23. The predicted amino acid sequence shows very high similarity to a subgroup of DEAD-box RNA helicases involved in ribosome biogenesis. This novel gene encodes a 3.2-kb transcript in a variety of human tissues. A processed pseudogene of DDX10 was detected at chromosome 9q21-q22. We observed a rare trinucleotide repeat length polymorphism within the coding sequence of DDX10.

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Year:  1996        PMID： 8660968     DOI： 10.1006/geno.1996.0184

Source DB:  PubMed          Journal:  Genomics        ISSN： 0888-7543            Impact factor:   5.736


  14 in total

1.  The rRNA-processing function of the yeast U14 small nucleolar RNA can be rescued by a conserved RNA helicase-like protein.

Authors:  W Q Liang; J A Clark; M J Fournier
Journal:  Mol Cell Biol       Date:  1997-07       Impact factor: 4.272

2.  Characterization of an extracellular lipase encoded by LIP2 in Yarrowia lipolytica.

Authors:  G Pignède; H Wang; F Fudalej; C Gaillardin; M Seman; J M Nicaud
Journal:  J Bacteriol       Date:  2000-05       Impact factor: 3.490

3.  Alterations of the PPP2R1B gene located at 11q23 in human colorectal cancers.

Authors:  Y Takagi; M Futamura; K Yamaguchi; S Aoki; T Takahashi; S Saji
Journal:  Gut       Date:  2000-08       Impact factor: 23.059

4.  Comparative genomic hybridization identifies loss of 18q22-qter as an early and specific event in tumorigenesis of midgut carcinoids.

Authors:  S Kytölä; A Höög; B Nord; B Cedermark; T Frisk; C Larsson; M Kjellman
Journal:  Am J Pathol       Date:  2001-05       Impact factor: 4.307

Review 5.  DEAD-ly Affairs: The Roles of DEAD-Box Proteins on HIV-1 Viral RNA Metabolism.

Authors:  Shringar Rao; Tokameh Mahmoudi
Journal:  Front Cell Dev Biol       Date:  2022-06-13

6.  Effects of the NUP98-DDX10 oncogene on primary human CD34+ cells: role of a conserved helicase motif.

Authors:  E R Yassin; A M Abdul-Nabi; A Takeda; N R Yaseen
Journal:  Leukemia       Date:  2010-03-25       Impact factor: 11.528

7.  Characterization and prediction of protein nucleolar localization sequences.

Authors:  Michelle S Scott; François-Michel Boisvert; Mark D McDowall; Angus I Lamond; Geoffrey J Barton
Journal:  Nucleic Acids Res       Date:  2010-07-26       Impact factor: 16.971

Review 8.  Dead-box proteins: a family affair--active and passive players in RNP-remodeling.

Authors:  Patrick Linder
Journal:  Nucleic Acids Res       Date:  2006-08-26       Impact factor: 16.971

9.  Alterations in the expression of DEAD-box and other RNA binding proteins during HIV-1 replication.

Authors:  Vyjayanthi Krishnan; Steven L Zeichner
Journal:  Retrovirology       Date:  2004-12-08       Impact factor: 4.602

10.  European multicenter study on LOH of APOC3 at 11q23 in 766 breast cancer patients: relation to clinical variables. Breast Cancer Somatic Genetics Consortium.

Authors:  V Launonen; K Laake; P Huusko; D Niederacher; M W Beckmann; R B Barkardottir; E K Geirsdottir; J Gudmundsson; P Rio; Y J Bignon; S Seitz; S Scherneck; I Bièche; M H Champème; D Birnbaum; G White; J Varley; M Sztán; E Olah; A Osorio; J Benitez; N Spurr; N Velikonja; B Peterlin; R Winqvist
Journal:  Br J Cancer       Date:  1999-05       Impact factor: 7.640
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