E Durán1, J Cabezos, M Ros, M Terre, F Zarzuela, J L Bada. 1. Institut Català de la Salut, Departamento de Genética y Microbiología, Facultad de Medicina, Universidad Autónoma de Barcelona.
Abstract
BACKGROUND: The aim of the present was to study the prevalence of infection and tuberculous disease as well as the fulfillment of secondary antituberculin chemoprophylaxis in immigrants according to their geographic origin. PATIENTS AND METHODS: A descriptive study was carried out of 1,489 immigrants under the age of 35 years attended in the Tropical and Imported Disease Unit Drassanes in Barcelona, Spain from 1989 to 1994. RESULTS: The patients were from 79 countries, with 81.7% being males and 18.3% females (p < 0.001) of a mean age 26.1 +/- 5.7 and 23.4 +/- 7.5 years, respectively. Forty-three percent of the cases presented Mantoux test response > or = 10 mm of induration. The highest percent of positivity was observed in patients from Subsaharian Africa (52%) followed by Eastern Europeans and Asians (44%), South and Central Americans (38%) and Middle East and Northern Africa (34%) (p < 0.001). Thirty-nine percent of the 359 patients who initiated secondary antituberculin chemoprophylaxis completed the 6 months of treatment with the highest fulfillment being found in Africans (49%) followed by Americans (42%) and Asians (39%). The lowest rate was observed in the Eastern Europeans (20%) (p < 0.001). Fifty-six percent of the patients abandoned secondary antituberculin prophylaxis within the first three months. Eighteen cases of active tuberculosis were diagnosed. CONCLUSIONS: The prevalence of tuberculous infection and disease is high immigrants in Barcelona, Spain. The fulfillment of chemoprophylaxis is low and abandoned early. These facts should be evaluated when designing prevention and control programs.
BACKGROUND: The aim of the present was to study the prevalence of infection and tuberculous disease as well as the fulfillment of secondary antituberculin chemoprophylaxis in immigrants according to their geographic origin. PATIENTS AND METHODS: A descriptive study was carried out of 1,489 immigrants under the age of 35 years attended in the Tropical and Imported Disease Unit Drassanes in Barcelona, Spain from 1989 to 1994. RESULTS: The patients were from 79 countries, with 81.7% being males and 18.3% females (p < 0.001) of a mean age 26.1 +/- 5.7 and 23.4 +/- 7.5 years, respectively. Forty-three percent of the cases presented Mantoux test response > or = 10 mm of induration. The highest percent of positivity was observed in patients from Subsaharian Africa (52%) followed by Eastern Europeans and Asians (44%), South and Central Americans (38%) and Middle East and Northern Africa (34%) (p < 0.001). Thirty-nine percent of the 359 patients who initiated secondary antituberculin chemoprophylaxis completed the 6 months of treatment with the highest fulfillment being found in Africans (49%) followed by Americans (42%) and Asians (39%). The lowest rate was observed in the Eastern Europeans (20%) (p < 0.001). Fifty-six percent of the patients abandoned secondary antituberculin prophylaxis within the first three months. Eighteen cases of active tuberculosis were diagnosed. CONCLUSIONS: The prevalence of tuberculous infection and disease is high immigrants in Barcelona, Spain. The fulfillment of chemoprophylaxis is low and abandoned early. These facts should be evaluated when designing prevention and control programs.
Authors: J R Villalbí; H Galdós-Tangüís; J A Caylà; P Casañas; A Ferrer; M Nebot Journal: J Epidemiol Community Health Date: 1999-02 Impact factor: 3.710