Literature DB >> 8653233

Patients' knowledge about their drug allergies.

J P Wyatt1.   

Abstract

OBJECTIVE: To investigate the nature and accuracy of information carried by patients about their drug allergies.
SUBJECTS: 2500 new adult patients.
SETTING: Accident and emergency department of a tertiary referral centre.
METHODS: Patients were questioned about drug allergies. Where they claimed allergies, general practitioners were contacted for corroboration.
RESULTS: 242 patients (9.7%) claimed 276 allergies; 32 different drugs were implicated. Penicillin was implicated most often (151 patients); 38 patients could not remember what they were allergic to; 21 described severe reactions, but four could not remember the drugs involved. Only seven patients carried evidence of their allergies. General practitioners were contacted about 240 of the drug allergies; only 114 were confirmed as described.
CONCLUSIONS: Many patients who believe themselves to have drug allergies are poorly informed about them. Emergency prescribing for these patients may risk anaphylaxis. The future acceptance of "Smart cards"would reduce this risk. In the meantime, patients with drug allergies should be strongly encouraged to carry evidence of their allergies.

Entities:  

Mesh:

Year:  1996        PMID: 8653233      PMCID: PMC1342651          DOI: 10.1136/emj.13.2.114

Source DB:  PubMed          Journal:  J Accid Emerg Med        ISSN: 1351-0622


  8 in total

1.  Nature and extent of penicillin side-reactions, with particular reference to fatalities from anaphylactic shock.

Authors:  O Idsoe; T Guthe; R R Willcox; A L de Weck
Journal:  Bull World Health Organ       Date:  1968       Impact factor: 9.408

Review 2.  Penicillin allergy: how to diagnose and when to treat.

Authors:  S T Holgate
Journal:  Br Med J (Clin Res Ed)       Date:  1988-04-30

Review 3.  Adverse reactions to penicillin. Part I.

Authors:  J E Erffmeyer
Journal:  Ann Allergy       Date:  1981-10

Review 4.  Penicillin hypersensitivity--a review.

Authors:  T H Sher
Journal:  Pediatr Clin North Am       Date:  1983-02       Impact factor: 3.278

5.  Allergy to penicillin.

Authors:  L Beeley
Journal:  Br Med J (Clin Res Ed)       Date:  1984-02-18

Review 6.  Drug allergy.

Authors:  M E Weiss
Journal:  Med Clin North Am       Date:  1992-07       Impact factor: 5.456

7.  Penicillin allergy: a study of incidence as reported by patients.

Authors:  J R Kerr
Journal:  Br J Clin Pract       Date:  1994 Jan-Feb

8.  Allergy to penicillin: fable or fact?

Authors:  S J Surtees; M G Stockton; T W Gietzen
Journal:  BMJ       Date:  1991-05-04
  8 in total
  2 in total

1.  Documenting Penicillin Allergy: The Impact of Inconsistency.

Authors:  Nirav S Shah; Jessica P Ridgway; Natasha Pettit; John Fahrenbach; Ari Robicsek
Journal:  PLoS One       Date:  2016-03-16       Impact factor: 3.240

2.  A UK hospital survey to explore healthcare professional views and attitudes to patients incorrectly labelled as penicillin allergic: an antibiotic stewardship patient safety project.

Authors:  Michael Wilcock; Neil Powell; Jonathan Sandoe
Journal:  Eur J Hosp Pharm       Date:  2018-05-24
  2 in total

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